Protein Alignment CG17528 and PHKG2

DIOPT Version :10

• Sequence 1: NP_001036462.1
• Gene: CG17528 / 3355134
• FlyBaseID: FBgn0261387
• Length: 748
• Species: Drosophila melanogaster
• Sequence 2: NP_000285.1
• Gene: PHKG2 / 5261
• HGNCID: 8931
• Length: 406
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 106/287 - (36%)
• Similarity: 168/287 - (58%)
• Gaps: 28/287 - (9%)

  Fly   467 NELP-----SNIRNTYSLGRIIGDGNFAIVFKIKHRQTGHSYALKIIDKNKCKGKEHYID----- 521
            :|||     ......|....:||.|..::|.:..||.|||.:|:||::....:.....::
Human     9 DELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAERLSPEQLEEVREA 73

  Fly   522 --AEVRVMKKL-NHPHIISLILSVDQNTNMYLVLEYVSGGDLFDAITQVTRFSENQSRIMIRHLG 583
              .|..::::: .|||||:||.|.:.::.|:||.:.:..|:|||.:|:....||.::|.::|.|.
Human    74 TRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLL 138

  Fly   584 AAMTYLHSMGIVHRDIKPENLLVKLDEHGNVLELKLADFGLAC--EVNDLLYAVCGTPTYVAPEI 646
            .|:::||:..|||||:||||:|  ||::   ::::|:|||.:|  |..:.|..:||||.|:||||
Human   139 EAVSFLHANNIVHRDLKPENIL--LDDN---MQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEI 198

  Fly   647 L------LEVGYGLKIDVWAAGIILYILLCGFPPFVAPDNQQEPLFDAIISGIYEFPDPYWSDIG 705
            |      ...|||.::|:||.|:||:.||.|.|||.  ..:|..:...|:.|.|:|..|.|.|..
Human   199 LKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFW--HRRQILMLRMIMEGQYQFSSPEWDDRS 261

  Fly   706 DGVRDLIANMLQADPDVRFTSEDILDH 732
            ..|:|||:.:||.||:.|.|:|..|.|
Human   262 STVKDLISRLLQVDPEARLTAEQALQH 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX1	156..239	CDD:340526
		Ubl1_cv_Nsp3_N-like	309..392	CDD:475130
		Protein Kinases, catalytic domain	477..734	CDD:473864	103/272 (38%)
PHKG2	NP_000285.1	STKc_PhKG2	13..291	CDD:271083	103/283 (36%)
		Calmodulin-binding (domain-N). /evidence=ECO:0000250	306..330
		Calmodulin-binding (domain-C). /evidence=ECO:0000250	346..370