Protein Alignment CG17528 and DCDC2

DIOPT Version :9

• Sequence 1: NP_001036462.1
• Gene: CG17528 / 3355134
• FlyBaseID: FBgn0261387
• Length: 748
• Species: Drosophila melanogaster
• Sequence 2: NP_001182539.1
• Gene: DCDC2 / 51473
• HGNCID: 18141
• Length: 476
• Species: Homo sapiens
• Alignment Length: 495
• Identity: 110/495 - (22%)
• Similarity: 174/495 - (35%)
• Gaps: 143/495 - (28%)

  Fly   129 SGSACLSNTPTADHIKKRIPSSRTPTRKALRIKFYRNGDRFYPGITIPVSNERYRSFERLFEDLT 193
            |||:..|:     |:.:.:..|         :..|||||.||.|..:.:..::..|||...:::|
Human     2 SGSSARSS-----HLSQPVVKS---------VLVYRNGDPFYAGRRVVIHEKKVSSFEVFLKEVT 52

  Fly   194 RLLEENVKIP-GAVRTIYN-LCGKKITSLDELEDGQSYVCSCNNENFKKVEYNTGSQPLSNLPLS 256
                ..|:.| ||||.||. ..|.:|..||:::.|.:||.. ..|.|||:.|         |.:.
Human    53 ----GGVQAPFGAVRNIYTPRTGHRIRKLDQIQSGGNYVAG-GQEAFKKLNY---------LDIG 103

  Fly   257 NSRSNSHRLAKCRPSSPLKNGLLAGSSPFPACGGGTGNGSPLIASRLS----DRVTVVHPRIVTL 317
            .        .|.||...:...:                 .|:|.||::    .|..:..|..:.|
Human   104 E--------IKKRPMEVVNTEV-----------------KPVIHSRINVSARFRKPLQEPCTIFL 143

  Fly   318 IRSGTKPRRIMRLLLNKRNSPSFDHVLTAITQVVRLDTGYVRKVFTLSGIPVVRLSDFFGSDDVF 382
            |.:|.......|||:.::....:||||..:|:.:.|.:|.|.:::||.| .:|.......:...:
Human   144 IANGDLINPASRLLIPRKTLNQWDHVLQMVTEKITLRSGAVHRLYTLEG-KLVESGAELENGQFY 207

  Fly   383 FAYGTERINTAEDFKLEAEEQRAINVIRKTMRTTGTTCKGPKPKMPIKSK-KVYPPLVDSEPFKA 446
            .|.|.::..     ||...|   :...:.|||            .|...| ...||:|.|...|.
Human   208 VAVGRDKFK-----KLPYSE---LLFDKSTMR------------RPFGQKASSLPPIVGSRKSKG 252

  Fly   447 ETTPEDDRHAALLTSTGMEINELPSNIRNTYSLGRIIGDGNFAIVFKIKHRQTGHSYALKIIDKN 511
            .   .:|||:.  ::.|...|..|..::.                 |.|..........|:....
Human   253 S---GNDRHSK--STVGSSDNSSPQPLKR-----------------KGKKEDVNSEKLTKLKQNV 295

  Fly   512 KCKGKEHYID-------------AEVRVMKKLNHPHIISLILSVDQN------------------ 545
            |.|..:..|.             :|.|...::.......:.:.|||.
Human   296 KLKNSQETIPNSDEGIFKAGAERSETRGAAEVQEDEDTQVEVPVDQRPAEIVDEEEDGEKANKDA 360

  Fly   546 ------TNMYLVLEYVSGGDLFDAITQVTRF---SENQSR 576
                  :.|...||...|.:..||..||...   ||.|:|
Human   361 EQKEDFSGMNGDLEEEGGREATDAPEQVEEILDHSEQQAR 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX	153..244	CDD:214711	31/92 (34%)
		DCX	308..396	CDD:214711	21/87 (24%)
		PKc_like	477..734	CDD:304357	23/140 (16%)
		S_TKc	477..734	CDD:214567	23/140 (16%)
DCDC2	NP_001182539.1	DCX	17..96	CDD:176357	30/92 (33%)
		DCX	134..221	CDD:214711	23/92 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	234..476		35/189 (19%)
		ASF1_hist_chap	<299..419	CDD:304562	18/102 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3757
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810