DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17528 and CaMKI

DIOPT Version :9

Sequence 1:	NP_001036462.1	Gene:	CG17528 / 3355134	FlyBaseID:	FBgn0261387	Length:	748	Species:	Drosophila melanogaster
Sequence 2:	NP_524622.1	Gene:	CaMKI / 43792	FlyBaseID:	FBgn0016126	Length:	405	Species:	Drosophila melanogaster

Alignment Length:	295	Identity:	109/295 - (36%)
Similarity:	174/295 - (58%)	Gaps:	24/295 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   465 EINELPSNIRNTYSLGRIIGDGNFAIVFKIKHRQT-GHSYALKIIDKNKCKGKEHYIDAEVRVMK 528
            |:|:..| |...|:|..::|.|.|:.|...:.:.: |..:|:|||||...||||..::.|:||::
  Fly    20 ELNKQVS-IEEKYNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDKKALKGKEESLENEIRVLR 83

  Fly   529 ---------------KLNHPHIISLILSVDQNTNMYLVLEYVSGGDLFDAITQVTRFSENQSRIM 578
                           :|.||:|:.|:.:.:..:.:|||:|.|:||:|||.|.:...::|..:..:
  Fly    84 RFSANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGELFDRIVEKGSYTEKDASHL 148

  Fly   579 IRHLGAAMTYLHSMGIVHRDIKPENLL-VKLDEHGNVLELKLADFGLA-CEVNDLLYAVCGTPTY 641
            ||.:..|:.|:|..|:||||:|||||| ...|:...::   ::||||: .|.:.::...||||.|
  Fly   149 IRQILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIM---ISDFGLSKMEDSGIMATACGTPGY 210

  Fly   642 VAPEILLEVGYGLKIDVWAAGIILYILLCGFPPFVAPDNQQEPLFDAIISGIYEFPDPYWSDIGD 706
            ||||:|.:..||..:|||:.|:|.||||||:|||.  |.....||..|:.|.:||..|||.:|.:
  Fly   211 VAPEVLAQKPYGKAVDVWSIGVISYILLCGYPPFY--DENDANLFAQILKGDFEFDSPYWDEISE 273

  Fly   707 GVRDLIANMLQADPDVRFTSEDILDHSWTIGNKGN 741
            ..:..|.|::....:.|:|.:..|.|:|..||:.:
  Fly   274 SAKHFIKNLMCVTVEKRYTCKQALGHAWISGNEAS 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX	153..244	CDD:214711
		DCX	308..396	CDD:214711
		PKc_like	477..734	CDD:304357	102/274 (37%)
		S_TKc	477..734	CDD:214567	102/274 (37%)
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	103/278 (37%)
CaMKI	NP_524622.1	S_TKc	31..302	CDD:214567	102/275 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.820