DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG17528 and Speg

DIOPT Version :9

Sequence 1:NP_001036462.1 Gene:CG17528 / 3355134 FlyBaseID:FBgn0261387 Length:748 Species:Drosophila melanogaster
Sequence 2:XP_038939815.1 Gene:Speg / 363256 RGDID:2124 Length:3269 Species:Rattus norvegicus


Alignment Length:920 Identity:192/920 - (20%)
Similarity:336/920 - (36%) Gaps:258/920 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 KVKINSLHCNDA-----VLSSLQASPSATSPQSV-PSKANVVTEASIIEKTNQPHNVQEDNNYNR 63
            |:.:.|:|.:|:     .||:::...:.::..:| ||.|.:.|.  ::|..    .|.|......
  Rat  1040 KLLLTSVHEDDSGVYTCKLSTVKDELTCSARLTVRPSLAPLFTR--LLEDV----EVLEGRAARL 1098

  Fly    64 DC-----DSPESSSSEQDKELDDLRNLHSSSLTNSVVVGKSTGSLNGVYSITSVTSETKTLESVV 123
            ||     ..|..:.:.....:::..||..          :..|.|:.:: |..|.||.:.|..|.
  Rat  1099 DCKISGTPPPSVTWTHFGHPVNESENLRL----------RQDGGLHSLH-IARVGSEDEGLYEVS 1152

  Fly   124 TTN------------------SASG-SACLSNTPT-------ADHIKKRIPSSRTP--------T 154
            .||                  :||| |:.|...|:       .|..:..||....|        .
  Rat  1153 ATNTHGQAHCSAQLYVEEPRTAASGPSSKLEKMPSIPEEPEHGDLERLSIPDFLRPLQDLEVGLA 1217

  Fly   155 RKAL-----------RIKFYRNGDRFYPGITIPVSNER----YRSFERL------------FEDL 192
            ::|:           .|.::.||.|      |..|::|    ||...||            ::.:
  Rat  1218 KEAMLECQVTGLPYPTISWFHNGHR------IQSSDDRRMTQYRDIHRLVFPAVGPQHAGVYKSV 1276

  Fly   193 -----------TRLLEENVKIPG---AVRTIYNLCGKKIT-------SLDELEDGQSYVCSCNNE 236
                       ..|...:| :||   ....:..:.|:.:|       |||...|..|...:..::
  Rat  1277 IANKLGKAACYAHLYVTDV-VPGPPDGAPQVVAVTGRMVTLSWNPPRSLDMAIDPDSLTYTVQHQ 1340

  Fly   237 ------------NFKKVEY-----NTGSQPLSNLPLSNSRSNSHRLAKCRPSSPLKNGLLAGSSP 284
                        ..::.|:     ..|...:..:..|:.:|:|...|   ||.|::  ||....|
  Rat  1341 VLGSDQWTALVTGLREPEWAATGLKKGLHHIFRVLSSSGKSSSKPSA---PSEPVQ--LLEHGPP 1400

  Fly   285 FPACGGGTGNGSPLIASRLSDRVTVV--HPRIVTLIRSGTKPRRIMR----LLLNKR------NS 337
            .        ..:|.:..: .|.|.||  .|..||:..:..:.:.:.|    .||..|      :.
  Rat  1401 L--------EEAPAVLDK-QDIVYVVEGQPACVTVTFNHVEAQVVWRSCRGALLEPRTGVYELSQ 1456

  Fly   338 PSFDHVLTAITQVVRLDTG----------------------------------------YVRKVF 362
            |..|.....|.:|.|.|.|                                        ..|...
  Rat  1457 PDDDQYCLRICRVSRRDLGPLTCSARNRHGTKACSITLELAEAPRFESIMEDVEVGPGETARFAV 1521

  Fly   363 TLSGIPV---------VRLSDFFGSDDVFFAYGTERINTAEDFKLEAEEQRAINVIRKTMRTTG- 417
            .:.|.|:         |.|::   |:.|.|.|   ..|......|.|..|.. .|...|.|... 
  Rat  1522 VVEGKPLPDIMWYKDEVLLAE---SNHVSFVY---EENECSLVVLSAGSQDG-GVYTCTARNLAG 1579

  Fly   418 -TTCKGPKPKMPIKSKKVYPPLVDSEPFKAETTPEDDRHAALLTSTGMEINELPSNIRNTYSLGR 481
             .:||.   ::.:.|.:.        ..:.|...||:.|      .|..:::.       |.:.:
  Rat  1580 EVSCKA---ELSVHSAQT--------AMEVEGVGEDEEH------RGRRLSDY-------YDIHQ 1620

  Fly   482 IIGDGNFAIVFKIKHRQTGHSYALKIID---KNKCKGKEHYIDAEVRVMKKLNHPHIISLILSVD 543
            .||.|.|:.:.::..|.:|..:|.|.|.   |.|...:.     |.|::.:|.|..::....:.:
  Rat  1621 EIGRGAFSYLRRVVERSSGLEFAAKFIPSQAKPKASARR-----EARLLARLQHDCVLYFHEAFE 1680

  Fly   544 QNTNMYLVLEYVSGGDLFDAITQVTRFSENQSRIMIRHLGAAMTYLHSMGIVHRDIKPENLLVKL 608
            :...:.:|.|..: .:|.:.:.:.....|:::|..:|.:...:.|||...::|.|:||||||| .
  Rat  1681 RRRGLVIVTELCT-EELLERMARKPTVCESETRTYMRQVLEGIGYLHQSHVLHLDVKPENLLV-W 1743

  Fly   609 DEHGNVLELKLADFGLACEV--NDLLYAVCGTPTYVAPEILLEVGYGLKIDVWAAGIILYILLCG 671
            |..|...::::.|||.|.|:  .:..|...|||.:|||||:.:.......|:|..|::.::.|.|
  Rat  1744 DGAGGEEQVRICDFGNAQELTPGEPQYCQFGTPEFVAPEIVNQSPVSGVTDIWPVGVVAFLCLTG 1808

  Fly   672 FPPFVAPDNQQEPLFDAIISGIYEFPDPYWSDIGDGVRDLIANMLQADPDVRFTSEDILDHSW-T 735
            ..|||. :|.:..|.: |.:....|.:..:..:....|..:..:|..| .:|.|:|:.|:|.| .
  Rat  1809 ISPFVG-ENDRTTLMN-IRNYNVAFEETTFLSLSREARGFLIKVLVQD-RLRPTAEETLEHPWFK 1870

  Fly   736 IGNKGNECTT 745
            ...||.|.:|
  Rat  1871 TEAKGAEVST 1880

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17528NP_001036462.1 DCX 153..244 CDD:214711 25/163 (15%)
DCX 308..396 CDD:214711 26/148 (18%)
PKc_like 477..734 CDD:304357 70/261 (27%)
S_TKc 477..734 CDD:214567 70/261 (27%)
SpegXP_038939815.1 I-set 45..127 CDD:400151
Ig strand A 45..47 CDD:409353
Ig strand A' 49..55 CDD:409353
Ig strand B 62..69 CDD:409353
Ig strand C 75..80 CDD:409353
Ig strand C' 82..85 CDD:409353
Ig strand F 106..114 CDD:409353
Ig strand G 117..127 CDD:409353
PHA03247 <324..681 CDD:223021
Ig strand A 736..739 CDD:409353
I-set 737..826 CDD:400151
Ig strand A' 742..746 CDD:409353
Ig strand B 754..762 CDD:409353
Ig strand C 767..772 CDD:409353
Ig strand C' 775..777 CDD:409353
Ig strand D 783..788 CDD:409353
Ig strand E 791..796 CDD:409353
Ig strand F 805..813 CDD:409353
Ig strand G 816..826 CDD:409353
SPEG_u2 827..883 CDD:293256
IgI_APEG-1_like 884..974 CDD:409567
Ig strand B 901..905 CDD:409567
Ig strand C 914..918 CDD:409567
Ig strand E 940..944 CDD:409567
Ig strand F 954..959 CDD:409567
Ig strand G 967..970 CDD:409567
Ig 988..1073 CDD:416386 6/32 (19%)
Ig strand A' 991..994 CDD:409353
Ig strand B 998..1007 CDD:409353
Ig strand C 1012..1018 CDD:409353
Ig strand C' 1021..1023 CDD:409353
Ig strand D 1030..1035 CDD:409353
Ig strand E 1038..1045 CDD:409353 1/4 (25%)
Ig strand F 1053..1060 CDD:409353 1/6 (17%)
Ig strand G 1063..1073 CDD:409353 0/9 (0%)
Ig 1079..1168 CDD:416386 19/105 (18%)
Ig strand A 1079..1082 CDD:409353 0/2 (0%)
Ig strand A' 1085..1090 CDD:409353 1/8 (13%)
Ig strand B 1095..1102 CDD:409353 2/6 (33%)
Ig strand C 1109..1115 CDD:409353 0/5 (0%)
Ig strand C' 1116..1119 CDD:409353 0/2 (0%)
Ig strand D 1124..1130 CDD:409353 2/15 (13%)
Ig strand E 1133..1143 CDD:409353 3/10 (30%)
Ig strand F 1147..1155 CDD:409353 2/7 (29%)
Ig strand G 1157..1168 CDD:409353 0/10 (0%)
I-set 1203..1292 CDD:400151 15/94 (16%)
Ig strand A 1203..1206 CDD:409353 1/2 (50%)
Ig strand A' 1209..1214 CDD:409353 0/4 (0%)
Ig strand B 1219..1226 CDD:409353 1/6 (17%)
Ig strand C 1233..1239 CDD:409353 1/5 (20%)
Ig strand C' 1240..1243 CDD:409353 2/8 (25%)
Ig strand D 1248..1254 CDD:409353 1/5 (20%)
Ig strand E 1257..1267 CDD:409353 2/9 (22%)
Ig strand F 1271..1279 CDD:409353 0/7 (0%)
Ig strand G 1281..1292 CDD:409353 1/10 (10%)
I-set 1500..1589 CDD:400151 18/98 (18%)
Ig strand A' 1508..1511 CDD:409353 0/2 (0%)
Ig strand B 1515..1524 CDD:409353 1/8 (13%)
Ig strand C 1529..1535 CDD:409353 0/5 (0%)
Ig strand C' 1538..1540 CDD:409353 1/1 (100%)
Ig strand D 1546..1551 CDD:409353 3/7 (43%)
Ig strand E 1554..1561 CDD:409353 0/6 (0%)
Ig strand F 1569..1576 CDD:409353 2/6 (33%)
Ig strand G 1579..1589 CDD:409353 2/12 (17%)
STKc_SPEG_rpt1 1613..1869 CDD:271010 70/272 (26%)
PHA03247 <1951..2352 CDD:223021
I-set 2594..2684 CDD:400151
Ig strand A 2594..2596 CDD:409353
Ig strand A' 2599..2604 CDD:409353
Ig strand B 2611..2619 CDD:409353
Ig strand C 2624..2628 CDD:409353
Ig strand D 2639..2646 CDD:409353
Ig strand E 2649..2654 CDD:409353
Ig strand F 2663..2671 CDD:409353
Ig strand G 2674..2684 CDD:409353
PHA03247 <2785..2910 CDD:223021
PKc_like 2964..3220 CDD:419665
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0032
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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