DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17528 and sqa

DIOPT Version :9

Sequence 1:	NP_001036462.1	Gene:	CG17528 / 3355134	FlyBaseID:	FBgn0261387	Length:	748	Species:	Drosophila melanogaster
Sequence 2:	NP_001260832.1	Gene:	sqa / 36002	FlyBaseID:	FBgn0259678	Length:	888	Species:	Drosophila melanogaster

Alignment Length:	258	Identity:	90/258 - (34%)
Similarity:	140/258 - (54%)	Gaps:	15/258 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   483 IGDGNFAIVFKIKHRQTGHSYALKIIDKNKCKGKEHYIDAEVRVMKKLNHPHIISLILSVDQNTN 547
            :|.|.|..|:|.:.:..|...|.|.:...|.:.|.: ::.||.:|..|.|..||.|..:.:....
  Fly    40 VGRGKFGTVYKCRDKANGLQLAAKFVPIPKREDKRN-VEREVEIMNSLQHHLIIQLYAAYEYQKM 103

  Fly   548 MYLVLEYVSGGDLFDAITQVTRF--SENQSRIMIRHLGAAMTYLHSMGIVHRDIKPENLLVKLDE 610
            |.:|||.:.||:|||.:.. ..|  :|...|:.||.:..||.::|..||||.|:||||:|| |.:
  Fly   104 MCVVLELIEGGELFDRVVD-DEFVLTERVCRVFIRQVCEAMAFIHGNGIVHLDLKPENILV-LTQ 166

  Fly   611 HGNVLELKLADFGLA--CEVNDLLYAVCGTPTYVAPEILLE--VGYGLKIDVWAAGIILYILLCG 671
            .||  .:|:.|||||  .:.:..|..:.|||.:||||::..  :.||  .|:|:.|:|.|:|:.|
  Fly   167 KGN--RIKIIDFGLARKFDPDKRLRVLFGTPEFVAPEVVNFDCISYG--TDMWSVGVICYVLISG 227

  Fly   672 FPPFVAPDNQQEPLFDAIISGIYEFPDPYWSDIGDGVRDLIANMLQADPDVRFTSEDILDHSW 734
            ..||:. :|..|.:.:..|:. |:|.|..::.|.....|.||.:|..|...|.|:.:.:.|.|
  Fly   228 LSPFMG-ENDIETMSNVTIAK-YDFEDECFNGISPECLDFIAKLLAKDLSTRMTAAECMKHKW 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX	153..244	CDD:214711
		DCX	308..396	CDD:214711
		PKc_like	477..734	CDD:304357	89/256 (35%)
		S_TKc	477..734	CDD:214567	89/256 (35%)
sqa	NP_001260832.1	S_TKc	34..289	CDD:214567	90/258 (35%)
sqa	NP_001260832.1	STKc_MLCK	40..289	CDD:271005	90/258 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900