DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17528 and mapkapk2a

DIOPT Version :9

Sequence 1:	NP_001036462.1	Gene:	CG17528 / 3355134	FlyBaseID:	FBgn0261387	Length:	748	Species:	Drosophila melanogaster
Sequence 2:	NP_958460.1	Gene:	mapkapk2a / 327321	ZFINID:	ZDB-GENE-030131-5532	Length:	382	Species:	Danio rerio

Alignment Length:	281	Identity:	94/281 - (33%)
Similarity:	152/281 - (54%)	Gaps:	34/281 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   473 IRNTYSL-GRIIGDGNFAIVFKIKHRQTGHSYALKIIDKNKCKGKEHYIDAEVRVMKKLNHPHII 536
            |.:.|.: .:::|.|....|.:|.::::|...|||::  :.|......::...|..   :..||:
Zfish    40 ITDDYKITNQVLGLGINGRVLEIFYKRSGEKLALKML--HDCPKARREVELHWRAS---SCTHIV 99

  Fly   537 SLILSVDQNTNMY-------LVLEYVSGGDLFDAITQ--VTRFSENQSRIMIRHLGAAMTYLHSM 592
            .:   ||...|:|       :|:|.:.||:||..|..  ...|:|.::..:::.:|.|:.|||::
Zfish   100 KI---VDVYENLYQNRKCLLIVMECMDGGELFSRIQDRGDQAFTEREASDIMKSIGEAIQYLHAI 161

  Fly   593 GIVHRDIKPENLLVKLDEHGNVLELKLADFGLACE--VNDLLYAVCGTPTYVAPEILLEVGYGLK 655
            .|.|||:||||||. ..:..|.| |||.|||.|.|  .::.|...|.||.|||||:|....|...
Zfish   162 NIAHRDVKPENLLY-TSKRPNAL-LKLTDFGFAKETTTHNSLATPCYTPYYVAPEVLGPEKYDKS 224

  Fly   656 IDVWAAGIILYILLCGFPPF-------VAPDNQQEPLFDAIISGIYEFPDPYWSDIGDGVRDLIA 713
            .|:|:.|:|:||||||:|||       ::|..::.     |..|.||||:|.||::.:..:.||.
Zfish   225 CDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKKR-----IRMGQYEFPNPEWSEVSEEAKQLIR 284

  Fly   714 NMLQADPDVRFTSEDILDHSW 734
            .:|:.:|..|.|..:.::|.|
Zfish   285 TLLKTEPTQRMTITEFMNHPW 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX	153..244	CDD:214711
		DCX	308..396	CDD:214711
		PKc_like	477..734	CDD:304357	92/275 (33%)
		S_TKc	477..734	CDD:214567	92/275 (33%)
mapkapk2a	NP_958460.1	STKc_MAPKAPK2	42..344	CDD:271072	93/279 (33%)
mapkapk2a	NP_958460.1	S_TKc	49..306	CDD:214567	92/272 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000