DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17528 and Camk1d

DIOPT Version :9

Sequence 1:	NP_001036462.1	Gene:	CG17528 / 3355134	FlyBaseID:	FBgn0261387	Length:	748	Species:	Drosophila melanogaster
Sequence 2:	NP_001100835.1	Gene:	Camk1d / 307124	RGDID:	1560691	Length:	385	Species:	Rattus norvegicus

Alignment Length:	270	Identity:	108/270 - (40%)
Similarity:	161/270 - (59%)	Gaps:	8/270 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   472 NIRNTYSLGRIIGDGNFAIVFKIKHRQTGHSYALKIIDKNKCKGKEHYIDAEVRVMKKLNHPHII 536
            :|:..:.....:|.|.|:.|...:.:.||..:|:|.|.|...||||..|:.|:.|::|:.|.:|:
  Rat    18 DIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIV 82

  Fly   537 SLILSVDQNTNMYLVLEYVSGGDLFDAITQVTRFSENQSRIMIRHLGAAMTYLHSMGIVHRDIKP 601
            :|....:...::|||::.||||:|||.|.:...::|..:..:||.:..|:.|||.|||||||:||
  Rat    83 ALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKP 147

  Fly   602 ENLL-VKLDEHGNVLELKLADFGLAC--EVNDLLYAVCGTPTYVAPEILLEVGYGLKIDVWAAGI 663
            |||| ...||...::   ::||||:.  ...|::...||||.|||||:|.:..|...:|.|:.|:
  Rat   148 ENLLYYSQDEESKIM---ISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGV 209

  Fly   664 ILYILLCGFPPFVAPDNQQEPLFDAIISGIYEFPDPYWSDIGDGVRDLIANMLQADPDVRFTSED 728
            |.||||||:|||.  |.....||:.|:...|||..|||.||.|..:|.|.|:::.||:.|:|.|.
  Rat   210 IAYILLCGYPPFY--DENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQ 272

  Fly   729 ILDHSWTIGN 738
            ...|.|..|:
  Rat   273 AARHPWIAGD 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX	153..244	CDD:214711
		DCX	308..396	CDD:214711
		PKc_like	477..734	CDD:304357	105/259 (41%)
		S_TKc	477..734	CDD:214567	105/259 (41%)
Camk1d	NP_001100835.1	STKc_CaMKI_delta	12..312	CDD:271070	108/270 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820