DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17528 and Phkg1

DIOPT Version :9

Sequence 1:	NP_001036462.1	Gene:	CG17528 / 3355134	FlyBaseID:	FBgn0261387	Length:	748	Species:	Drosophila melanogaster
Sequence 2:	NP_113761.1	Gene:	Phkg1 / 29353	RGDID:	3325	Length:	388	Species:	Rattus norvegicus

Alignment Length:	306	Identity:	105/306 - (34%)
Similarity:	163/306 - (53%)	Gaps:	45/306 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   447 ETTPEDDRHAALLTSTGMEINELPSNIRNTYSLGRIIGDGNFAIVFKIKHRQTGHSYALKIIDKN 511
            |..|  |.|:|             .|....|....|:|.|..::|.:..|:.|...||:||||
  Rat     5 EALP--DSHSA-------------QNFYENYEPKEILGRGVSSVVRRCIHKPTCQEYAVKIID-- 52

  Fly   512 KCKGKEHYIDAEVR-----------VMKKLN-HPHIISLILSVDQNTNMYLVLEYVSGGDLFDAI 564
             ..|...:...||:           :::|:: ||:||.|..:.:.||..:||.:.:..|:|||.:
  Rat    53 -ITGGGSFSSEEVQELREATLKEVDILQKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYL 116

  Fly   565 TQVTRFSENQSRIMIRHLGAAMTYLHSMGIVHRDIKPENLLVKLDEHGNVLELKLADFGLACEV- 628
            |:....:|.::|.::|.|...:..||.:.|||||:||||:|  ||::.|:   ||.|||.:|::
  Rat   117 TEKVTLTEKETRKIMRALLEVVCTLHKLNIVHRDLKPENIL--LDDNMNI---KLTDFGFSCQLQ 176

  Fly   629 -NDLLYAVCGTPTYVAPEILL------EVGYGLKIDVWAAGIILYILLCGFPPFVAPDNQQEPLF 686
             .:.|..|||||:|:||||:.      ..|||.::|:|:.|:|:|.||.|.|||.  ..:|..:.
  Rat   177 PGEKLREVCGTPSYLAPEIIQCSMDEGHPGYGKEVDMWSTGVIMYTLLAGSPPFW--HRKQMLML 239

  Fly   687 DAIISGIYEFPDPYWSDIGDGVRDLIANMLQADPDVRFTSEDILDH 732
            ..|:.|.|:|..|.|.|..|.|:||::..|...|..|.::|:.|.|
  Rat   240 RMIMDGKYQFGSPEWDDYSDTVKDLVSRFLVVQPQDRCSAEEALAH 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX	153..244	CDD:214711
		DCX	308..396	CDD:214711
		PKc_like	477..734	CDD:304357	99/276 (36%)
		S_TKc	477..734	CDD:214567	99/276 (36%)
Phkg1	NP_113761.1	PKc_like	16..291	CDD:419665	99/280 (35%)
		Calmodulin-binding (domain-N)	303..327
		Calmodulin-binding (domain-C)	343..367
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920