DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17528 and Mapkapk2

DIOPT Version :9

Sequence 1:	NP_001036462.1	Gene:	CG17528 / 3355134	FlyBaseID:	FBgn0261387	Length:	748	Species:	Drosophila melanogaster
Sequence 2:	NP_835203.1	Gene:	Mapkapk2 / 289014	RGDID:	631362	Length:	386	Species:	Rattus norvegicus

Alignment Length:	332	Identity:	108/332 - (32%)
Similarity:	170/332 - (51%)	Gaps:	47/332 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   422 GPKPKMPIKSKKVYPPLVDSEPFKAETTPEDDRHAALLTSTGMEINELPSNIRNTYSL-GRIIGD 485
            |..|..|..|.   ||...::|    ..|....|    ..:|::|.:  :.|.:.|.: .:::|.
  Rat     7 GQTPPAPFPSP---PPPAPAQP----PPPFPQFH----VKSGLQIRK--NAITDDYKVTSQVLGL 58

  Fly   486 GNFAIVFKIKHRQTGHSYALKIIDKNKCKGKEHYIDAEVRVMKKLNHPHIISLILSVDQNTNMY- 549
            |....|.:|..::|...:|||::  ..|......::...|..:   .|||:.:   ||...|:|
  Rat    59 GINGKVLRIFDKRTQQKFALKML--QDCPKARREVELHWRASQ---CPHIVHI---VDVYENLYA 115

  Fly   550 ------LVLEYVSGGDLFDAITQ--VTRFSENQSRIMIRHLGAAMTYLHSMGIVHRDIKPENLLV 606
                  :|:|.:.||:||..|..  ...|:|.::..:::.:|.|:.||||:.|.|||:||||||.
  Rat   116 GRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLY 180

  Fly   607 KLDEHGNVLELKLADFGLACEV--NDLLYAVCGTPTYVAPEILLEVGYGLKIDVWAAGIILYILL 669
             ..:..|.: |||.|||.|.|.  ::.|...|.||.|||||:|....|....|:|:.|:|:||||
  Rat   181 -TSKRPNAI-LKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILL 243

  Fly   670 CGFPPF-------VAPDNQQEPLFDAIISGIYEFPDPYWSDIGDGVRDLIANMLQADPDVRFTSE 727
            ||:|||       ::|..:..     |..|.||||:|.||::.:.|:.||.|:|:.:|..|.|..
  Rat   244 CGYPPFYSNHGLAISPGMKTR-----IRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTIT 303

  Fly   728 DILDHSW 734
            :.::|.|
  Rat   304 EFMNHPW 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX	153..244	CDD:214711
		DCX	308..396	CDD:214711
		PKc_like	477..734	CDD:304357	95/275 (35%)
		S_TKc	477..734	CDD:214567	95/275 (35%)
Mapkapk2	NP_835203.1	STKc_MAPKAPK2	47..349	CDD:271072	96/279 (34%)
Mapkapk2	NP_835203.1	S_TKc	54..311	CDD:214567	95/272 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000