DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17528 and Uhmk1

DIOPT Version :9

Sequence 1:	NP_001036462.1	Gene:	CG17528 / 3355134	FlyBaseID:	FBgn0261387	Length:	748	Species:	Drosophila melanogaster
Sequence 2:	NP_058989.1	Gene:	Uhmk1 / 246332	RGDID:	2968	Length:	419	Species:	Rattus norvegicus

Alignment Length:	296	Identity:	77/296 - (26%)
Similarity:	127/296 - (42%)	Gaps:	63/296 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   478 SLGRI------IGDGNFAIVFKIKHRQTGHS--YALKIIDKNKCKG-----KEHYIDAEVRVMKK 529
            :.||:      :|.|:.|.|::::...|..|  .|||........|     .|:....|...:::
  Rat    18 AFGRLWQVQSRLGSGSSASVYRVRCCGTPGSPPGALKQFLPPGTTGAAASAAEYGFRKERAALEQ 82

  Fly   530 L-NHPHIISL--ILSVDQNTNM---YLVLEYVSGGDLFD-AITQVTRFSENQ--SRIMIRHLG-- 583
            | .|.:|::|  :.::..:.|:   .|:||      |.| :::::..:|.:|  |..||:|..
  Rat    83 LQGHRNIVTLYGVFTIHFSPNVPSRCLLLE------LLDVSVSELLVYSSHQGCSMWMIQHCARD 141

  Fly   584 --AAMTYLHSMGIVHRDIKPENLLVKLDEHGNVLELKLADFGLACEVNDLLYAVCGTPTYVAPEI 646
              .|:.:||..|.||.|:||.|:|...:...    .||.||||:.:..:.......|..|.|||.
  Rat   142 VLEALAFLHHEGYVHADLKPRNILWSAENEC----FKLIDFGLSFKEGNQDVKYIQTDGYRAPEA 202

  Fly   647 LLE---VGYGLK--------IDVWAAGIILYILLCGFP-PFVAPDNQQEPLFDAIISGIY----- 694
            .|:   ...||:        :|:|:.||||..:..|.. .......:.:....|||..|:
  Rat   203 ELQNCLAQAGLQSDTECTSAVDLWSLGIILLEMFSGMKLKHTVRSQEWKANSSAIIDHIFASKAV 267

  Fly   695 ---EFPDPYWSDIGDGVRDLIANMLQADPDVRFTSE 727
               ..|..:       :||||.:||..||..|..:|
  Rat   268 VNAAIPAYH-------LRDLIKSMLHDDPSRRIPAE 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX	153..244	CDD:214711
		DCX	308..396	CDD:214711
		PKc_like	477..734	CDD:304357	77/296 (26%)
		S_TKc	477..734	CDD:214567	77/296 (26%)
Uhmk1	NP_058989.1	STKc_KIS	22..308	CDD:270922	75/292 (26%)
Uhmk1	NP_058989.1	RRM_UHMK1	318..405	CDD:409898
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900