DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17528 and Camkv

DIOPT Version :9

Sequence 1:	NP_001036462.1	Gene:	CG17528 / 3355134	FlyBaseID:	FBgn0261387	Length:	748	Species:	Drosophila melanogaster
Sequence 2:	NP_663596.1	Gene:	Camkv / 235604	MGIID:	2384296	Length:	512	Species:	Mus musculus

Alignment Length:	282	Identity:	95/282 - (33%)
Similarity:	153/282 - (54%)	Gaps:	14/282 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   470 PSNIRNTYSLGRIIGDGNFAIVFKIKHRQTGHSYALKIIDKNKCKGKEHYIDAEVRVMKKLNHPH 534
            ||.:.:.|.||::|....|..:|:.|.:.||..:..|...|...:........|:.::|.:.||:
Mouse    17 PSEVTDRYDLGQVIKTEEFCEIFRAKDKTTGKLHTCKKFQKRDGRKVRKAAKNEIGILKMVKHPN 81

  Fly   535 IISLILSVDQNTNMYLVLEYVSGGDLFDAITQVTRFSENQSRIMIRHLGAAMTYLHSMGIVHRDI 599
            |:.|:.........::.||..:|.::||.|.....:||..:..::|.:..|:.||||:.||||::
Mouse    82 ILQLVDVFVTRKEYFIFLELATGREVFDWILDQGYYSERDTSNVVRQVLEAVAYLHSLKIVHRNL 146

  Fly   600 KPENLLVKLDEHGNVL---ELKLADFGLACEVNDLLYAVCGTPTYVAPEILLEVGYGLKIDVWAA 661
            |.|||:     :.|.|   ::.::||.||...|.|:...||||.|:|||::....||..:|.||.
Mouse   147 KLENLV-----YYNRLKNSKIVISDFHLAKLENGLIKEPCGTPEYLAPEVVGRQRYGRPVDCWAI 206

  Fly   662 GIILYILLCGFPPFVAP------DNQQEPLFDAIISGIYEFPDPYWSDIGDGVRDLIANMLQADP 720
            |:|:||||.|.|||...      :|..:.||..|::|.|||..|||.||....:||:..:::.:.
Mouse   207 GVIMYILLSGNPPFYEEVEEDDYENHDKNLFRKILAGDYEFDSPYWDDISQAAKDLVTRLMEVEQ 271

  Fly   721 DVRFTSEDILDHSWTIGNKGNE 742
            |.|.|:|:.:.|.|..||..::
Mouse   272 DQRITAEEAISHEWISGNAASD 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX	153..244	CDD:214711
		DCX	308..396	CDD:214711
		PKc_like	477..734	CDD:304357	90/265 (34%)
		S_TKc	477..734	CDD:214567	90/265 (34%)
Camkv	NP_663596.1	STKc_CaMK_like	22..286	CDD:270990	90/268 (34%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	328..347
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	393..512
		DUF5585	397..>511	CDD:375359
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820