Protein Alignment CG17528 and Mylk2

DIOPT Version :9

• Sequence 1: NP_001036462.1
• Gene: CG17528 / 3355134
• FlyBaseID: FBgn0261387
• Length: 748
• Species: Drosophila melanogaster
• Sequence 2: NP_001074513.2
• Gene: Mylk2 / 228785
• MGIID: 2139434
• Length: 613
• Species: Mus musculus
• Alignment Length: 576
• Identity: 134/576 - (23%)
• Similarity: 226/576 - (39%)
• Gaps: 133/576 - (23%)

  Fly   244 NTGSQPLSNLPLSNSRSNSHRLAKCRPSSPLKNGLLAGSSPFPAC------------GGGTGNGS 296
            |....|.:..|.:|....|.:....:...|.|.|     .|.||.            |||...||
Mouse    49 NAKKDPGAPDPKNNPDPPSLKKDPAKAPGPEKKG-----DPVPASASSQGPSGEGDGGGGPAEGS 108

  Fly   297 -------PLIASRLSDRVTVVHPRIVTL-------IRSGTKPRRIMRLLLNKRNSPSFDH----- 342
                   ||..:.....:..:.|.....       .::|.|......  ..:|.||:|.|
Mouse   109 EGPPAALPLPTATAEASIQKLDPTQAPSGNQGSGEAKAGKKAAECRE--AGRRGSPAFLHSPSCP 171

  Fly   343 -VLTAI--TQVVRLDTGYVRKVFTLSGIPVV--------------------------RLSDFFGS 378
             :::..  |..|:..:.....|||  |:.|.                          :.|...|.
Mouse   172 AIISCSEKTLAVKPLSETTDLVFT--GVSVTPDPQDPGPVKAGGTNALAEKKKEEAEKASGQAGQ 234

  Fly   379 DDV---------FFAYGTERINTAEDFKLEAEEQRAINVIRKTMRTTGTTCKGPKPKMPIKSKKV 434
            ..|         |.|..:||:...:...|.|.|:....::        ..|  |.|..|
Mouse   235 AKVQGDTPQRIGFQAVPSERVEVGQALCLTAREEDCFQIL--------DDC--PPPPAP------ 283

  Fly   435 YPPLVDSEPFKAETTPEDDRHAALLTSTGMEINELPSNIRNTYSLG--RIIGDGNFAIVFKIKHR 497
            :|                  |..:...||        |:.:.:|:.  ..:|.|.|..|.....|
Mouse   284 FP------------------HRIVELRTG--------NVNSEFSMNSKEALGGGKFGAVCTCTER 322

  Fly   498 QTGHSYALKIIDKNKCKGKEHYIDAEVRVMKKLNHPHIISLILSVDQNTNMYLVLEYVSGGDLFD 562
            .||...|.|:|.|...|.||..: .|:.||.:|||.::|.|..:::.:..:.|.:||:.||:||:
Mouse   323 ATGLKLAAKVIKKQTPKDKEMVL-LEIEVMNQLNHRNLIQLYAAIETSHEIILFMEYIEGGELFE 386

  Fly   563 AIT-QVTRFSENQSRIMIRHLGAAMTYLHSMGIVHRDIKPENLLVKLDEHGNVLELKLADFGLA- 625
            .|. :....:|..:.:.:|.:...:.::|.|.::|.|:||||:|. ::..|::  :|:.|||||
Mouse   387 RIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILC-VNTTGHL--VKIIDFGLAR 448

  Fly   626 -CEVNDLLYAVCGTPTYVAPEILLEVGYGLKIDVWAAGIILYILLCGFPPFVAPDNQQEPLFDAI 689
             ...|:.|....|||.:::||::.......|.|:|:.|:|.|:||.|..||:..|:.:  ..:.:
Mouse   449 RYNPNEKLKVNFGTPEFLSPEVVNYDQISDKTDMWSLGVITYMLLSGLSPFLGDDDTE--TLNNV 511

  Fly   690 ISGIYEFPDPYWSDIGDGVRDLIANMLQADPDVRFTSEDILDHSW--TIGNKGNEC 743
            :|..:.|.:..:..:.|..:|.::|:|..|...|.::|..|.|.|  .:..|...|
Mouse   512 LSANWYFDEETFEAVSDEAKDFVSNLLTKDQSARMSAEQCLAHPWLNNLAEKAKRC 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX	153..244	CDD:214711	134/576 (23%)
		DCX	308..396	CDD:214711	22/137 (16%)
		PKc_like	477..734	CDD:304357	79/261 (30%)
		S_TKc	477..734	CDD:214567	79/261 (30%)
Mylk2	NP_001074513.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..168		26/125 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	219..240		3/20 (15%)
		STKc_MLCK2	298..557	CDD:271092	79/264 (30%)
		S_TKc	308..557	CDD:214567	78/254 (31%)
		Calmodulin-binding. /evidence=ECO:0000250	591..603

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900