DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17528 and Y50D7A.3

DIOPT Version :9

Sequence 1:	NP_001036462.1	Gene:	CG17528 / 3355134	FlyBaseID:	FBgn0261387	Length:	748	Species:	Drosophila melanogaster
Sequence 2:	NP_001368037.1	Gene:	Y50D7A.3 / 190101	WormBaseID:	WBGene00021753	Length:	426	Species:	Caenorhabditis elegans

Alignment Length:	303	Identity:	90/303 - (29%)
Similarity:	152/303 - (50%)	Gaps:	31/303 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   458 LLTSTGMEINELPSNIRN--------TYSLGRIIGDGNFAIVFKIKHRQTGHSYALKIID----- 509
            |:..|..|.::...:.|:        .|....::|.|..:.|.:...:.:|..:|:||:|
Worm     4 LIVDTDHEDSDESQHYRHEEDQGFNAAYESKEVLGRGLASTVRRCIEKGSGQHFAVKIVDISTEK 68

  Fly   510 --KNKCKGKEHYIDAEVRVMKKLN-HPHIISLILSVDQNTNMYLVLEYVSGGDLFDAITQVTRFS 571
              :|:.|.......:||.::::|: ||.||.:.......:.::.|.|....|:|||.:......|
Worm    69 QSENEAKRLLEETISEVEILRQLSGHPSIIKIHDFYQTPSFLFAVFEMAPRGELFDVLNSTVTVS 133

  Fly   572 ENQSRIMIRHLGAAMTYLHSMGIVHRDIKPENLLVKLDEHGNVLELKLADFGLACEV--NDLLYA 634
            |.::|.:::.|...:.|:|:..|||||:|.||:|. :||.    .:.::|||.|..:  ...|..
Worm   134 EKRARRLMKQLFDGVEYMHARDIVHRDLKLENILC-IDEE----RIVISDFGFATRIPRGKKLRD 193

  Fly   635 VCGTPTYVAPEILL------EVGYGLKIDVWAAGIILYILLCGFPPFVAPDNQQEPLFDAIISGI 693
            :||||.|:|||.:.      ..||.|::|.||.|:|:|.||.|..||.  ..:|..:...|..|.
Worm   194 LCGTPGYLAPETIRCQWYDNAEGYSLEVDEWALGVIMYTLLAGCAPFY--HRKQLMMLRLIQQGK 256

  Fly   694 YEFPDPYWSDIGDGVRDLIANMLQADPDVRFTSEDILDHSWTI 736
            :||.:..|::|....::||..:||.|...|.:|::.|.|.|.|
Worm   257 FEFRNEQWANITAEAKNLITQLLQVDATKRISSKECLAHEWMI 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX	153..244	CDD:214711
		DCX	308..396	CDD:214711
		PKc_like	477..734	CDD:304357	84/272 (31%)
		S_TKc	477..734	CDD:214567	84/272 (31%)
Y50D7A.3	NP_001368037.1	STKc_PhKG	27..298	CDD:270995	84/277 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920