DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17528 and F32D8.1

DIOPT Version :9

Sequence 1:	NP_001036462.1	Gene:	CG17528 / 3355134	FlyBaseID:	FBgn0261387	Length:	748	Species:	Drosophila melanogaster
Sequence 2:	NP_505770.3	Gene:	F32D8.1 / 185203	WormBaseID:	WBGene00009326	Length:	333	Species:	Caenorhabditis elegans

Alignment Length:	275	Identity:	101/275 - (36%)
Similarity:	156/275 - (56%)	Gaps:	11/275 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   472 NIRNTYSLGRIIGDGNFAIVFKIKHRQTGHSYALKIIDKNKCKGKEHYIDAEVRVMKKLNHPHII 536
            :|...|.:|.|||.|||:.|...:.::.|...|||.::|...:||..::|.||.::..:.|.|||
Worm    66 DIEKQYEIGAIIGKGNFSSVHLTRRKEDGTKCALKQVEKRAMRGKCFFVDNEVEMLSLIQHDHII 130

  Fly   537 SLILSVDQNTNMYLVLEYVSGGDLFDAITQVTRFSENQSRIMIRHLGAAMTYLHSMGIVHRDIKP 601
            |:|.:.......::|.|:...|||::.|.:..|..|..:.|:...:.:|:.|||...:||||:||
Worm   131 SIIDAFSTENQYFIVFEHAQYGDLYETIRKNGRIEEPDAAIITLQVASALNYLHERNVVHRDVKP 195

  Fly   602 ENLLVKLDEHGNVLELKLADFGLACEVNDLLYAVCGTPTYVAPEILLEVGYGLKIDVWAAGIILY 666
            ||||: :|:    ..:||.||||||.:...||.:||||||.|||:|.|.||..:.|:|:.|::||
Worm   196 ENLLL-VDK----FSVKLCDFGLACHILGPLYRICGTPTYCAPEVLRETGYSTRCDIWSLGVVLY 255

  Fly   667 ILLCGFPPFVAPDNQQEPLFDAIISGIYEFPDPYWSDIGDGVRDLIANMLQADPDVRFTSEDILD 731
            ::|.|:.||.|||  |..||..|:........|.|..|....:||::.::....:.|..:..|:.
Worm   256 VMLVGYAPFRAPD--QTRLFKLIMQAKPNLDMPEWKGISLKAKDLVSRLMNKTEERRPLASQIMA 318

  Fly   732 HSW----TIGNKGNE 742
            |.|    |:.|..:|
Worm   319 HPWIAPYTMENIDDE 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX	153..244	CDD:214711
		DCX	308..396	CDD:214711
		PKc_like	477..734	CDD:304357	96/256 (38%)
		S_TKc	477..734	CDD:214567	96/256 (38%)
F32D8.1	NP_505770.3	STKc_CAMK	70..321	CDD:270687	96/257 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810