DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17528 and mlck-1

DIOPT Version :9

Sequence 1:	NP_001036462.1	Gene:	CG17528 / 3355134	FlyBaseID:	FBgn0261387	Length:	748	Species:	Drosophila melanogaster
Sequence 2:	NP_509689.1	Gene:	mlck-1 / 181217	WormBaseID:	WBGene00013869	Length:	1211	Species:	Caenorhabditis elegans

Alignment Length:	321	Identity:	95/321 - (29%)
Similarity:	159/321 - (49%)	Gaps:	35/321 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   423 PKPKMPIKSKKVYPPLVDSEP-FKAETTPEDDRHAALLTSTGMEINELPSNIR--NTYSLGRIIG 484
            |.....||..:.||..:|..| |..:                 :|..:.:|::  ..|.:.:::|
Worm     5 PSGSGKIKVDEHYPSELDEPPVFDVK-----------------KIENIRANVKFDTLYQVTKLLG 52

  Fly   485 DGNFAIVFKIKHRQTGHSYALKIIDKNKCKGKEHYIDAEVRVMKKLNHPHIISLILSVDQNTN-M 548
            ||.|..|:.:..::||..:|.|.| |.:.:.....::.||.::.:|.||.|..:..:....|| :
Worm    53 DGKFGKVYCVIEKETGKEFAAKFI-KIRKEADRAEVEREVSILTQLRHPRIAQIYDAFYTTTNDV 116

  Fly   549 YLVLEYVSGGDLFDAITQVTR-FSENQSRIMIRHLGAAMTYLHSMGIVHRDIKPENLL-VKLDEH 611
            .|::|.|.||:|||.:.:.:. .||....::|..|..|:.|:|...|:|.|:||||:: |.|.
Worm   117 VLIMEIVRGGELFDRVAEESYVLSELAVVMIICQLCEAIDYIHKQNILHLDVKPENIMCVSLT-- 179

  Fly   612 GNVLELKLADFGLACE---VNDLLYAVCGTPTYVAPEILLEVGYGLKIDVWAAGIILYILLCGFP 673
            ||  .:||.|||||..   ..:|.| :.|||.:.|||::.........|:|:.|:|.||||.|:.
Worm   180 GN--RIKLIDFGLARHYDGTQELKY-MAGTPEFAAPEVIKFEKLDYHTDMWSIGVITYILLSGYS 241

  Fly   674 PFVAPDNQQEPLFDAIISGIYEFPDPYWSDIGDGVRDLIANMLQADPDVRFTSEDILDHSW 734
            ||:. ||..| .:..:..|::||.:.: ..:.:..:|.:..:|..|...|....:.|.|.|
Worm   242 PFLG-DNLGE-TYCNVEKGVWEFTEEF-DTVTEEAKDFVTKLLVYDQSKRMLPHECLQHPW 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX	153..244	CDD:214711
		DCX	308..396	CDD:214711
		PKc_like	477..734	CDD:304357	84/262 (32%)
		S_TKc	477..734	CDD:214567	84/262 (32%)
mlck-1	NP_509689.1	PKc_like	51..300	CDD:389743	84/258 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900