DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17528 and Camk1

DIOPT Version :9

Sequence 1:	NP_001036462.1	Gene:	CG17528 / 3355134	FlyBaseID:	FBgn0261387	Length:	748	Species:	Drosophila melanogaster
Sequence 2:	XP_006237061.1	Gene:	Camk1 / 171503	RGDID:	629473	Length:	414	Species:	Rattus norvegicus

Alignment Length:	271	Identity:	108/271 - (39%)
Similarity:	165/271 - (60%)	Gaps:	10/271 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   472 NIRNTYSLGRIIGDGNFAIVFKIKHRQTGHSYALKIIDKNKCKGKEHYIDAEVRVMKKLNHPHII 536
            :||:.|....::|.|.|:.|...:.::|....|:|.|.|...:|||..::.|:.|:.|:.||:|:
  Rat    46 DIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKKALEGKEGSMENEIAVLHKIKHPNIV 110

  Fly   537 SLILSVDQNTNMYLVLEYVSGGDLFDAITQVTRFSENQSRIMIRHLGAAMTYLHSMGIVHRDIKP 601
            :|....:...::||:::.||||:|||.|.:...::|..:..:|..:..|:.|||.:||||||:||
  Rat   111 ALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKP 175

  Fly   602 ENLL-VKLDEHGNVLELKLADFGLACEVND---LLYAVCGTPTYVAPEILLEVGYGLKIDVWAAG 662
            |||| ..|||...::   ::||||: ::.|   :|...||||.|||||:|.:..|...:|.|:.|
  Rat   176 ENLLYYSLDEDSKIM---ISDFGLS-KMEDPGSVLSTACGTPGYVAPEVLAQKPYSKAVDCWSIG 236

  Fly   663 IILYILLCGFPPFVAPDNQQEPLFDAIISGIYEFPDPYWSDIGDGVRDLIANMLQADPDVRFTSE 727
            :|.||||||:|||.  |.....||:.|:...|||..|||.||.|..:|.|.::::.||:.|||.|
  Rat   237 VIAYILLCGYPPFY--DENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCE 299

  Fly   728 DILDHSWTIGN 738
            ..|.|.|..|:
  Rat   300 QALQHPWIAGD 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX	153..244	CDD:214711
		DCX	308..396	CDD:214711
		PKc_like	477..734	CDD:304357	104/260 (40%)
		S_TKc	477..734	CDD:214567	104/260 (40%)
Camk1	XP_006237061.1	STKc_CaMKI_alpha	47..309	CDD:271069	107/267 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820