Protein Alignment CG17528 and EFHB

DIOPT Version :9

• Sequence 1: NP_001036462.1
• Gene: CG17528 / 3355134
• FlyBaseID: FBgn0261387
• Length: 748
• Species: Drosophila melanogaster
• Sequence 2: NP_653316.3
• Gene: EFHB / 151651
• HGNCID: 26330
• Length: 833
• Species: Homo sapiens
• Alignment Length: 589
• Identity: 116/589 - (19%)
• Similarity: 193/589 - (32%)
• Gaps: 195/589 - (33%)

  Fly    27 ATSPQSVP-------SKANVVTEASIIEKTNQPHNVQEDNNYNRDCDSPESSSSEQDKELDDLRN 84
            |..||..|       ||.:|:....|                     :|:..::.|.|..|...:
Human   312 ANDPQIAPYLTHGIRSKISVLANTLI---------------------NPQPITTFQQKIKDKKES 355

  Fly    85 LHSSSLTNSVVVGKSTGSLNGVYSITSVTSETKTLESVVTTNSASGSACLSNTPTADHIKKRIPS 149
            ::.|:  ....:|||.....|:         .|.::   |||:..|:|.:......|.:..  |.
Human   356 IYLSN--RRAPLGKSHDQAPGL---------PKGMD---TTNTTFGTAVIKEYSAKDVVNP--PK 404

  Fly   150 SRTPTRKALRIKFYRNGDR-----------FYPGITIPVSNERYR--SFERLFEDLTRLLEENVK 201
            |..        :.::.|:.           :|.|   ...|.:|.  ||.|            ..
Human   405 SYE--------EVFKEGNEGHDLYVVSHNDYYAG---EAKNRKYNPSSFHR------------CS 446

  Fly   202 IPGAVRTIYN---LCGKKITSLDELE--DGQSYVCSCNNENFK-KVEYNTGS--QPLS---NLPL 255
            :.|.....:|   ...|.:..|.||:  .|..:| |...::|| |.::..|.  .|::   |:|
Human   447 VYGVPTPHFNDGRAMAKSLYWLHELQMKRGAKFV-SKRADDFKEKFQHKLGRVLDPIAETMNVP- 509

  Fly   256 SNSRSNSHRLAKCRPSSPLKNGLLAGSSPFPAC----GGGTGNGSPLIASRLSDRVTVVHPRIVT 316
                      ..|               .|.||    ..|.|:   ||.:||.|.
Human   510 ----------PDC---------------TFGACLRPEEYGVGD---LIHNRLPDE---------- 536

  Fly   317 LIRSGTKPRRI---MRLLLNKRNSPSFDHVLTAITQVVRLDTGYVRK----------VFTLSGIP 368
            .:|...:.|.:   :|..|.|.|...||.:|.|.....:...|.:.|          ..:|....
Human   537 YLRGKDRQRALIAAVRHHLKKVNYQKFDTLLAAFRHYDKKGDGMIDKDELQEACDQANLSLDDKL 601

  Fly   369 VVRLSDFFGSD-DVFFAY--GTERINTAEDFKLEAEEQRAINVIRK--TMRTTGTTCKGPKPKMP 428
            :.:|.|:...| |.|..|  ....:|..:...|:..|:|.|...||  .:..|....:.|:..:.
Human   602 LDQLFDYCDVDNDGFINYLEFANFLNWKDKMLLKEYEERVIIKGRKPDCVNPTEANVEEPEQTLL 666

  Fly   429 IKSKKVYPPLVDSEPFKAETT-----PEDDRHAALLTSTGMEIN----ELPS---------NIRN 475
            ||.:.:    |..|....|.|     ...|:.:....:|..|||    .:||         .||:
Human   667 IKPEDI----VLKEAGSTEKTLRTLLRPSDKVSNYYKTTSSEINAIVGAIPSTCYPICGVPTIRS 727

  Fly   476 TYSLGRI--IGDGNFAIVFKIKHRQTGHSYAL---------KIIDKN--KCKGKEHYIDAEVRVM 527
            .....||  |.|       :..:.:.|.:|:|         .:.:::  |.:.||...:....:.
Human   728 DIPAPRIRRISD-------RTNYGEEGSAYSLLYPTIFARKGVFERDFFKTRSKEEIAEILCNIG 785

  Fly   528 KKLN 531
            .||:
Human   786 VKLS 789

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX	153..244	CDD:214711	20/109 (18%)
		DCX	308..396	CDD:214711	20/103 (19%)
		PKc_like	477..734	CDD:304357	12/68 (18%)
		S_TKc	477..734	CDD:214567	12/68 (18%)
EFHB	NP_653316.3	EF-hand_7	566..626	CDD:290234	11/59 (19%)
		EFh	566..626	CDD:238008	11/59 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900