DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17528 and Phkg2

DIOPT Version :9

Sequence 1:	NP_001036462.1	Gene:	CG17528 / 3355134	FlyBaseID:	FBgn0261387	Length:	748	Species:	Drosophila melanogaster
Sequence 2:	NP_542151.1	Gene:	Phkg2 / 140671	RGDID:	620024	Length:	406	Species:	Rattus norvegicus

Alignment Length:	297	Identity:	112/297 - (37%)
Similarity:	174/297 - (58%)	Gaps:	28/297 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   467 NELP-----SNIRNTYSLGRIIGDGNFAIVFKIKHRQTGHSYALKII----DKNKCKGKEHYIDA 522
            :|||     ......|....|||.|..::|.:..||.||..:|:||:    ::...:..|...||
  Rat     9 DELPDWAAAKEFYQKYDPKDIIGRGVSSVVRRCVHRATGDEFAVKIMEVSAERLSLEQLEEVRDA 73

  Fly   523 ---EVRVMKKL-NHPHIISLILSVDQNTNMYLVLEYVSGGDLFDAITQVTRFSENQSRIMIRHLG 583
               |:.::::: .|||||:||.|.:.::.|:||.:.:..|:|||.:|:....||.::|.::|.|.
  Rat    74 TRREMHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLL 138

  Fly   584 AAMTYLHSMGIVHRDIKPENLLVKLDEHGNVLELKLADFGLAC--EVNDLLYAVCGTPTYVAPEI 646
            .|:.:||...|||||:||||:|  ||::   ::::|:|||.:|  |..:.|..:||||.|:||||
  Rat   139 EAVNFLHVNNIVHRDLKPENIL--LDDN---MQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEI 198

  Fly   647 L------LEVGYGLKIDVWAAGIILYILLCGFPPFVAPDNQQEPLFDAIISGIYEFPDPYWSDIG 705
            |      ...|||.::|:||.|:||:.||.|.|||.  ..:|..:...|:.|.|:|..|.|.|..
  Rat   199 LKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFW--HRRQILMLRMIMEGQYQFSSPEWDDRS 261

  Fly   706 DGVRDLIANMLQADPDVRFTSEDILDHSWTIGNKGNE 742
            :.|:||||.:||.||:.|.|:|..|.|.:....||::
  Rat   262 NTVKDLIAKLLQVDPNARLTAEQALQHPFFERCKGSQ 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX	153..244	CDD:214711
		DCX	308..396	CDD:214711
		PKc_like	477..734	CDD:304357	107/272 (39%)
		S_TKc	477..734	CDD:214567	107/272 (39%)
Phkg2	NP_542151.1	STKc_PhKG2	13..291	CDD:271083	107/284 (38%)
		Calmodulin-binding (domain-N). /evidence=ECO:0000250	306..330
		Calmodulin-binding (domain-C). /evidence=ECO:0000250	346..370
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920