DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17528 and Dcx

DIOPT Version :9

Sequence 1:	NP_001036462.1	Gene:	CG17528 / 3355134	FlyBaseID:	FBgn0261387	Length:	748	Species:	Drosophila melanogaster
Sequence 2:	NP_001103692.1	Gene:	Dcx / 13193	MGIID:	1277171	Length:	366	Species:	Mus musculus

Alignment Length:	386	Identity:	135/386 - (34%)
Similarity:	198/386 - (51%)	Gaps:	89/386 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 ELD----DLRNLHSSSLTNSVVVGKSTGSLNGVYSITSVTS----ETKTLESVVTTNSASGSACL 134
            |||    |.|:..|.::..|        .:||:.|.|....    .|:||::            |
Mouse     2 ELDFGHFDERDKASRNMRGS--------RMNGLPSPTHSAHCSFYRTRTLQA------------L 46

  Fly   135 SNTPTADHIKKRIPSSRTPTRKALRIKFYRNGDRFYPGITIPVSNERYRSFERLFEDLTRLLEEN 199
            ||                 .:||.:::|||||||::.||...||::|:|||:.|..||||.|.:|
Mouse    47 SN-----------------EKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDN 94

  Fly   200 VKIPGAVRTIYNLCG-KKITSLDELEDGQSYVCSCNNENFKKVEYNTGSQPLSNLPLSNSRSNSH 263
            :.:|..||.||.:.| :||.|:||||:|:|||||.:| .||||||.....|..::   |.:::::
Mouse    95 INLPQGVRYIYTIDGSRKIGSMDELEEGESYVCSSDN-FFKKVEYTKNVNPNWSV---NVKTSAN 155

  Fly   264 RLAKCRPSSPLKNGLLAGSSPFPACGGGTGNGSPLIASRLSDRVTVVHPRIVTLIRSGTKPRRIM 328
            ..|   |.|      ||.|:                :::..:....|.|::||:||||.|||:.:
Mouse   156 MKA---PQS------LASSN----------------SAQARENKDFVRPKLVTIIRSGVKPRKAV 195

  Fly   329 RLLLNKRNSPSFDHVLTAITQVVRLDTGYVRKVFTLSGIPVVRLSDFFGSDDVFFAYGTERINTA 393
            |:||||:.:.||:.|||.||:.::|:||.|:|::||.|..|..|.||||.||||.|.|.|:...|
Mouse   196 RVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFRYA 260

  Fly   394 -EDFKLEAEEQRAINVIRKTMRTTGTTCKGPKPK-MPIKSKKVYPPLVDSEPFKAETTPED 452
             :||.|:..|.|       .|:...:...|||.. .|.|:....|     .|.:...:|.|
Mouse   261 QDDFSLDENECR-------VMKGNPSAAAGPKASPTPQKTSAKSP-----GPMRRSKSPAD 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX	153..244	CDD:214711	49/91 (54%)
		DCX	308..396	CDD:214711	45/88 (51%)
		PKc_like	477..734	CDD:304357
		S_TKc	477..734	CDD:214567
Dcx	NP_001103692.1	DCX1_DCX	51..139	CDD:340529	49/88 (56%)
		DCX2	176..259	CDD:340589	44/82 (54%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	275..366		9/40 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	70	1.000	Domainoid score	I9505
eggNOG	1	0.900	-	-		E1_KOG3757
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291886at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm43763
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.780