DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17528 and Dapk2

DIOPT Version :9

Sequence 1:	NP_001036462.1	Gene:	CG17528 / 3355134	FlyBaseID:	FBgn0261387	Length:	748	Species:	Drosophila melanogaster
Sequence 2:	XP_036010488.1	Gene:	Dapk2 / 13143	MGIID:	1341297	Length:	490	Species:	Mus musculus

Alignment Length:	292	Identity:	105/292 - (35%)
Similarity:	166/292 - (56%)	Gaps:	14/292 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   457 ALLTSTGMEINELPSNIRNTYSLGRIIGDGNFAIVFKIKHRQTGHSYALKIIDKNKCKGK----- 516
            |.:.|..||..: ...:.:.|.:|..:|.|.||||.|.:.:.||..||.|.|.|.:.:..
Mouse     4 ASMRSPNMETFK-QQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVC 67

  Fly   517 EHYIDAEVRVMKKLNHPHIISLILSVDQNTNMYLVLEYVSGGDLFDAITQVTRFSENQSRIMIRH 581
            ...|:.||.:::::.||:||:|....:..|::.|:||.||||:|||.:.|....||.::...|:.
Mouse    68 REEIEREVSILRQVLHPNIITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQ 132

  Fly   582 LGAAMTYLHSMGIVHRDIKPENLLVKLDEHGNVLELKLADFGLACEVND--LLYAVCGTPTYVAP 644
            :...:.|||:..|.|.|:||||::: ||::..:..:||.|||||.|:.|  ....:.|||.:|||
Mouse   133 ILDGVNYLHTKKIAHFDLKPENIML-LDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAP 196

  Fly   645 EILLEVGYGLKIDVWAAGIILYILLCGFPPFVAPDNQQEPLFDAIISGI-YEFPDPYWSDIGDGV 708
            ||:.....||:.|:|:.|:|.||||.|..||:. |.:||.|  |.|:.: |:|.:.::|...:..
Mouse   197 EIVNYEPLGLEADMWSIGVITYILLSGASPFLG-DTKQETL--ANITAVSYDFDEEFFSQTSELA 258

  Fly   709 RDLIANMLQADPDVRFTSEDILDHSWTIGNKG 740
            :|.|..:|..:...|.|.::.|.|.| |.:||
Mouse   259 KDFIRKLLVKETRKRLTIQEALRHPW-ITSKG 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX	153..244	CDD:214711
		DCX	308..396	CDD:214711
		PKc_like	477..734	CDD:304357	97/264 (37%)
		S_TKc	477..734	CDD:214567	97/264 (37%)
Dapk2	XP_036010488.1	STKc_DAPK2	17..285	CDD:271098	98/272 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810