DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17528 and Camk4

DIOPT Version :9

Sequence 1:	NP_001036462.1	Gene:	CG17528 / 3355134	FlyBaseID:	FBgn0261387	Length:	748	Species:	Drosophila melanogaster
Sequence 2:	XP_006525606.1	Gene:	Camk4 / 12326	MGIID:	88258	Length:	497	Species:	Mus musculus

Alignment Length:	337	Identity:	117/337 - (34%)
Similarity:	171/337 - (50%)	Gaps:	35/337 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   416 TGTTCKGPKPKMPIKSKKVYPPLVDSEPFKAETTPEDDRHAALLTSTGMEINELP------SN-- 472
            :|...:.|..||    .||..|...|.|..:.|...:              |.:|      ||
Mouse    18 SGGVFRSPAAKM----LKVTVPSCPSSPCSSVTASTE--------------NLVPDYWIDGSNRD 64

  Fly   473 -IRNTYSLGRIIGDGNFAIVFKIKHRQTGHSYALKIIDKNKCKGKEHYIDAEVRVMKKLNHPHII 536
             :.:.:.:...:|.|..:||::.|.:.|...||||::.|...|   ..:..|:.|:.:|:||:||
Mouse    65 PLGDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDK---KIVRTEIGVLLRLSHPNII 126

  Fly   537 SLILSVDQNTNMYLVLEYVSGGDLFDAITQVTRFSENQSRIMIRHLGAAMTYLHSMGIVHRDIKP 601
            .|....:..|.:.||||.|:||:|||.|.:...:||..:...::.:..|:.|||..||||||:||
Mouse   127 KLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKP 191

  Fly   602 ENLLVKLDEHGNVLELKLADFGLA--CEVNDLLYAVCGTPTYVAPEILLEVGYGLKIDVWAAGII 664
            ||||.......  ..||:|||||:  .|...|:..|||||.|.|||||....||.::|:|:.|||
Mouse   192 ENLLYATPAPD--APLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGII 254

  Fly   665 LYILLCGFPPFVAPDNQQEPLFDAIISGIYEFPDPYWSDIGDGVRDLIANMLQADPDVRFTSEDI 729
            .|||||||.||. .:...:.:|..|::..|.|..|:|.::....:||:..::..||..|.|:...
Mouse   255 TYILLCGFEPFY-DERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVKKLIVLDPKKRLTTFQA 318

  Fly   730 LDHSWTIGNKGN 741
            |.|.|..|...|
Mouse   319 LQHPWVTGKAAN 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX	153..244	CDD:214711
		DCX	308..396	CDD:214711
		PKc_like	477..734	CDD:304357	100/258 (39%)
		S_TKc	477..734	CDD:214567	100/258 (39%)
Camk4	XP_006525606.1	STKc_CaMKIV	66..359	CDD:270987	103/271 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24349
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920