Protein Alignment CG17528 and dclk2

DIOPT Version :10

• Sequence 1: NP_001036462.1
• Gene: CG17528 / 3355134
• FlyBaseID: FBgn0261387
• Length: 748
• Species: Drosophila melanogaster
• Sequence 2: XP_012811056.1
• Gene: dclk2 / 100487296
• XenbaseID: XB-GENE-960488
• Length: 727
• Species: Xenopus tropicalis
• Alignment Length: 681
• Identity: 277/681 - (40%)
• Similarity: 389/681 - (57%)
• Gaps: 111/681 - (16%)

  Fly   125 TNSASGSACLSN---TPTADH------IKKRIPSSRTPTRKALRIKFYRNGDRFYPGITIPVSNE 180
            ::|:|||....|   .|:..|      .:.|...:.:..|||.:::|||||||::.|:...||.|
 Frog    30 SSSSSGSGHRGNHGLIPSPAHSAHCSFYRTRTLQALSSERKAKKVRFYRNGDRYFKGLPYAVSAE 94

  Fly   181 RYRSFERLFEDLTRLLEENVKIPGAVRTIYNLCG-KKITSLDELEDGQSYVCSCNNENFKKVEYN 244
            |:||.:.|..:|||.|.:||.:|..||.||.|.| |||.||:||::|:||||: :||.::||:||
 Frog    95 RFRSLDALLMELTRSLSDNVSLPQGVRCIYTLDGNKKIGSLEELQEGESYVCA-SNEPYRKVDYN 158

  Fly   245 TGSQPLSNLPLSNSRSNSHRLAKCRPSSPLKNGLLAGSSPFPACGGGTGNGSPLIA-----SRLS 304
            ....|..::   |.|                                ||:|..|.|     :.:.
 Frog   159 RNVSPNWSV---NVR--------------------------------TGSGRSLSALMTLKNEMK 188

  Fly   305 DRVTVVHPRIVTLIRSGTKPRRIMRLLLNKRNSPSFDHVLTAITQVVRLDTGYVRKVFTLSGIPV 369
            :....:.|::||:||||:|||:.:|:||||:.:.||:.|||.||:.::||:|.|:::.||.|..|
 Frog   189 ESKDYIKPKLVTVIRSGSKPRKAVRILLNKKTAHSFEQVLTDITEAIKLDSGVVKRLCTLDGKQV 253

  Fly   370 VRLSDFFGSDDVFFAYGTERINTA-EDFKLEAEEQRAINVIRKTMRTTGTTCKGPKP---KMPIK 430
            ..|.||||.||||.|.|.|:...| :||.|:.|        .:.::|..:  :.|:|   |.|..
 Frog   254 TCLQDFFGEDDVFIACGPEKYRYAQDDFVLDHE--------CRVLKTAYS--RSPRPPGSKSPGT 308

  Fly   431 SKKVYPPL--------------VDSEPFKAETTPEDDRHA------------------------- 456
            |::...|.              |:..|....:||:..:.:
 Frog   309 SRRSKSPASVRRGGHYSSTKSPVNGTPSSQLSTPKSTKSSCSSPTSPGSFRGLRIPPHCGSTSNV 373

  Fly   457 -ALLTS-TGMEINEL--PSNIRNTYSLGRIIGDGNFAIVFKIKHRQTGHSYALKIIDKNKCKGKE 517
             .||.| .|:..|:.  .|.|...|.:|::|||||||:|.:...|.||..:|||||||.||.|||
 Frog   374 NGLLNSPEGLNGNKFTDASIILEKYKIGKVIGDGNFAVVKECVERSTGKEFALKIIDKAKCCGKE 438

  Fly   518 HYIDAEVRVMKKLNHPHIISLILSVDQNTNMYLVLEYVSGGDLFDAITQVTRFSENQSRIMIRHL 582
            |.|:.||.:::::.||:||.||..:|....:|||:|.|.|||||||||..|:::|..:..|:.:|
 Frog   439 HLIENEVSILRQVKHPNIIMLIEEMDTTAELYLVMELVKGGDLFDAITSSTKYTERDASAMVYNL 503

  Fly   583 GAAMTYLHSMGIVHRDIKPENLLVKLDEHGNVLELKLADFGLACEVNDLLYAVCGTPTYVAPEIL 647
            .:||.|||.:.||||||||||||| .:.......|||.|||||..|:..||.||||||||||||:
 Frog   504 ASAMKYLHGLHIVHRDIKPENLLV-CEYPDKTKSLKLGDFGLATVVDGPLYTVCGTPTYVAPEII 567

  Fly   648 LEVGYGLKIDVWAAGIILYILLCGFPPFVAPDNQQEPLFDAIISGIYEFPDPYWSDIGDGVRDLI 712
            .|.|||||:|:||||:|.||||||||||.:.:|.||.|||.|:.|..|||.|||.:|.|..::||
 Frog   568 AETGYGLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILIGKLEFPSPYWDNITDSAKELI 632

  Fly   713 ANMLQADPDVRFTSEDILDHSWTI--GNKGN 741
            :.|||.:.:.|:|:|.||.|.|..  .::||
 Frog   633 SCMLQVNVEERYTAEQILSHPWVSDDASQGN 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX1	156..239	CDD:340526	44/83 (53%)
		Ubl1_cv_Nsp3_N-like	309..392	CDD:475130	42/82 (51%)
		Protein Kinases, catalytic domain	477..734	CDD:473864	144/256 (56%)
dclk2	XP_012811056.1	DCX1_DCLK2	70..154	CDD:340661	44/84 (52%)
		DCX2	193..276	CDD:340589	42/82 (51%)
		STKc_DCKL2	396..654	CDD:271086	144/258 (56%)