DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17528 and si:ch73-60h1.1

DIOPT Version :9

Sequence 1:	NP_001036462.1	Gene:	CG17528 / 3355134	FlyBaseID:	FBgn0261387	Length:	748	Species:	Drosophila melanogaster
Sequence 2:	XP_002663771.2	Gene:	si:ch73-60h1.1 / 100332381	ZFINID:	ZDB-GENE-140106-152	Length:	438	Species:	Danio rerio

Alignment Length:	272	Identity:	101/272 - (37%)
Similarity:	163/272 - (59%)	Gaps:	14/272 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   471 SNIRNTYSLGRIIGDGNFAIVFKIKHRQTGHSYALKIIDKNKCKGKEHYIDAEVRVMKKLNHPHI 535
            :.:.:.|::|..:|.|..::|.:.:.:||...||:|::.|...|   ..:..|:.|:.:|:||:|
Zfish    22 ATVEDFYNMGPELGRGATSVVLRCEEKQTEKPYAVKVLKKTIDK---KIVRTEIGVLLRLSHPNI 83

  Fly   536 ISLILSVDQNTNMYLVLEYVSGGDLFDAITQVTRFSENQSRIMIRHLGAAMTYLHSMGIVHRDIK 600
            |.|....:..|.::|:||.|:||:|||.|.:...:||..:..:|:.:..|:.|||..|:||||:|
Zfish    84 IRLKEIFETETEIFLILELVTGGELFDRIVERGYYSERDAAHVIKQILEAVAYLHENGVVHRDLK 148

  Fly   601 PENLL---VKLDEHGNVLELKLADFGLACEVND--LLYAVCGTPTYVAPEILLEVGYGLKIDVWA 660
            |||||   :.:|     ..||:|||||:..:::  .:..|||||.|.|||||....||.::|:|:
Zfish   149 PENLLYADLSID-----APLKIADFGLSKIIDEQVTMKTVCGTPGYCAPEILRGNAYGPEVDMWS 208

  Fly   661 AGIILYILLCGFPPFVAPDNQQEPLFDAIISGIYEFPDPYWSDIGDGVRDLIANMLQADPDVRFT 725
            .|:|||||||||.||......|. ::..|::..|||..|:|.::....:||:..::..||..|.|
Zfish   209 VGVILYILLCGFEPFFDQRGDQY-MYSRILNCDYEFVSPWWDEVSLNAKDLVNKLIVLDPHKRLT 272

  Fly   726 SEDILDHSWTIG 737
            .:..|:|.|.:|
Zfish   273 VKQALEHPWVLG 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX	153..244	CDD:214711
		DCX	308..396	CDD:214711
		PKc_like	477..734	CDD:304357	99/261 (38%)
		S_TKc	477..734	CDD:214567	99/261 (38%)
si:ch73-60h1.1	XP_002663771.2	STKc_CaMKIV	24..317	CDD:270987	101/270 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR24349
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.920