Protein Alignment conu and STARD8

DIOPT Version :9

• Sequence 1: NP_001036454.1
• Gene: conu / 3355133
• FlyBaseID: FBgn0039994
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_005262371.1
• Gene: STARD8 / 9754
• HGNCID: 19161
• Length: 1107
• Species: Homo sapiens
• Alignment Length: 615
• Identity: 132/615 - (21%)
• Similarity: 245/615 - (39%)
• Gaps: 148/615 - (24%)

  Fly    38 EDGEMEAEW--------------LVSAG--------YPEL--TKPFEQGLEVSKKDLEPILTTLS 78
            |||...|:|              ..|.|        .|||  .:|...|.|...:|.|.  :..|
Human   326 EDGHRLADWQPGRRWGCEGRRGSCGSTGSHASTYDNLPELYPAEPVMVGAEAEDEDDEE--SGGS 388

  Fly    79 KPHAEAIVQLVRTLNKTVRVRTKSRPKRKPDIRDVFREFDEQGT-----VTRSRSATPDSLDSLQ 138
            ..|.:.|:|.|..|.:.|.:.:::   ..||:.....| :|:.|     .|.......::|..::
Human   389 YAHLDDILQHVWGLQQRVELWSRA---MYPDLGPGDEE-EEEATSSVEIATVEVKCQAEALSQME 449

  Fly   139 I-----DEAWTNNSLPTFVNVYEKNTETAIQCVEQSNEIYLKQNLRRTPSAPPKSGTYADIFRGS 198
            :     ..||....:...|....:....|....::..|....     .|:..|...:..:...|.
Human   450 VPAHGESPAWAQAEVQPAVLAPAQAPAEAEPVAQEEAEAPAP-----APAPAPAQDSEQEAHSGG 509

  Fly   199 QVRCDIPLYSADGVELLGYSRIGTIQFPRNRSVSDPFCSIGRSKESRSENDARSQKKKSSEV--L 261
            :     |.:::            ::......|:||   ::..|.|..|..::.::.:.:..:  |
Human   510 E-----PTFAS------------SLSVEEGHSISD---TVASSSELDSSGNSMNEAEAAGPLAGL 554

  Fly   262 SAS------ENECGRLLPMPYNVL---SFESICRDSSSLDSCEVLDTCDIPSTLFT-DVVLISET 316
            .||      ::..|..|..|...|   ||::..|.|.:.:|.|:       :..|. .:.|:.:.
Human   555 QASMPRERRDSGVGASLTRPCRKLRWHSFQNSHRPSLNSESLEI-------NRQFAGQINLLHKG 612

  Fly   317 DMKRLQTILWLELATIFDRN--KVSLDKRKPFKRRRKEEG----NLFGVSINALIRRDQQVTGTD 375
            .:.||..  ::|..|:..:.  ..|:.|   |.||.|...    ::|||.....::|..|.
Human   613 SLLRLTA--FMEKYTVPHKQGWVWSMPK---FMRRNKTPDYRGQHVFGVPPLIHVQRTGQP---- 668

  Fly   376 SSLVPLFLEKLIGELLRRGSREEGLLRIGGHKQKTELLYNELESTFYQNPDNLDNLFRTATVHEL 440
               :|..:::.:..|..:...:.|:.|..|.|.:.:.| .::..|   :|||:  .:...:.:::
Human   669 ---LPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNL-RQMNET---SPDNV--CYEGQSAYDV 724

  Fly   441 SSLLKRWLRELPQPLLTNELIQLFYQCHTLPSIDQ-MNALSILCHLLPPENRNTLRSLLSFFNII 504
            :.|||::.|:||:|:.|::|...|.|.:.|...|| :.|......|||.|||..|::||.|.:.|
Human   725 ADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAAQAATLLLPDENREVLQTLLYFLSDI 789

  Fly   505 INLKDINKMNVHNVATIMAPSMF------------------------PPRYIHPSDNNSIAEQV- 544
            .:.:: |:|...|:|..:|||:|                        .||.:  |||.:..:.:
Human   790 ASAEE-NQMTAGNLAVCLAPSIFHLNVSKKDSPSPRIKSKRSLIGRPGPRDL--SDNMAATQGLS 851

  Fly   545 RMAAQCCRLTNILILRGEKLFQVPNNLIVE 574
            .|.:.|           :||||||.:::::
Human   852 HMISDC-----------KKLFQVPQDMVLQ 870

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	63/245 (26%)
STARD8	XP_005262371.1	SAM_superfamily	31..90	CDD:301707
		RhoGAP	653..867	CDD:295372	63/240 (26%)
		START_STARD8-like	894..1098	CDD:176916

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.900