Protein Alignment conu and Arhgap10

DIOPT Version :9

• Sequence 1: NP_001036454.1
• Gene: conu / 3355133
• FlyBaseID: FBgn0039994
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_084389.2
• Gene: Arhgap10 / 78514
• MGIID: 1925764
• Length: 786
• Species: Mus musculus
• Alignment Length: 582
• Identity: 120/582 - (20%)
• Similarity: 218/582 - (37%)
• Gaps: 144/582 - (24%)

  Fly    60 EQGLEVSKKDLEPILTTLSKPHAEAIVQLVRTLNKTVRVRTKSRPKRKPDIRDVFREFDEQ---- 120
            |:.::.|.::....|..|.:......:.:..||.|.:.   |.|.::...:::..::||::
Mouse    80 ERCIDASLREFSNFLKNLEEQREIMALSVTETLIKPLE---KFRKEQLGAVKEEKKKFDKETEKN 141

  Fly   121 -GTVTRSRSATPDSLDS------LQIDEAWTNNSLPTFVNVYEKNTETAIQCVEQSNEIYLKQNL 178
             ..:.:..:.:....||      ||:::   |..     :.|    |.:::.|.:..||   |..
Mouse   142 YSLIDKHLTLSARKKDSHLQEADLQVEQ---NRQ-----HFY----ELSLEYVCKLQEI---QER 191

  Fly   179 RRTPSAPPKSGTYADIF----RGSQVRCDIPLYSADGVELLGYSRIGTIQFPRNRSVSDPFCSIG 239
            ::.....|....:..:|    :|.::..|...|..: :::       .||..|||....
Mouse   192 KKFEFVEPMLSFFQGMFTFYHQGHELSKDFNHYKME-LQI-------NIQNTRNRFEGT------ 242

  Fly   240 RSKESRSENDAR---SQKKKSSEVLSASENECGRLLPMP------------------YNVLSFE- 282
            ||:.....|..|   ..:|::|:..:..........|.|                  :|::.||
Mouse   243 RSEVEELMNKIRQNPKDQKRASQFTAEGYLYVQEKRPAPFGSSWVKHYCMYRKTAKKFNMIPFEH 307

  Fly   283 --------------SIC----RDSSSLDSCEVLDTCDIPSTLFTDVVLISETDMKRLQTILWLEL 329
                          ..|    .||:....|..::..|.|....| |...||.:.|:     |||
Mouse   308 RSGGKLGDGEAFFLKECTKRHMDSTDRRFCFDIEAADRPGVPLT-VQAFSEEERKQ-----WLE- 365

  Fly   330 ATIFDRNKVSLDKRKPFKRRRKEEGNLFGVSINALIRRDQQVTGTDSSLVPLFLEKLIGELLRRG 394
                     :|..::.          ||.....|::.|.:.....|.....: |.|.|..:..||
Mouse   366 ---------ALGGKEA----------LFHTFNRAIVPRPEGGAQLDKMGFTI-LRKCISAVETRG 410

  Fly   395 SREEGLLRIGGHKQKTELLYNELESTFYQNPDNLDNLFRTA--TVHELSSLLKRWLRELPQPLLT 457
            ..::||.|:.|...|.:.|.:.|......|..:|:|   :|  .|..::|.||::||.||:||:|
Mouse   411 INDQGLYRVVGVSSKVQRLLSMLMDVKMCNELDLEN---SADWEVKTVTSALKQYLRSLPEPLMT 472

  Fly   458 NELIQLFYQCHTLPS-----IDQMNALSILCHLLPPENRNTLRSLLSFFNIIINLKDINKMNVHN 517
            .||.:.|    .:|:     ..::||:..|.|.||.:|:..|..|:.....:.:....|.|.|.|
Mouse   473 YELHRDF----IVPAKSGSPESRVNAIHFLVHKLPEKNKEMLDILVKHLTNVSSHSKQNLMTVAN 533

  Fly   518 VATIMAPSMFPPRYIHPSDNNSIAEQVRMAAQCCRLTN----ILILRGEKLFQV-PNNLIVE 574
            :..:..|::..|:           |:...|....:..|    |||...||:|:. |:....|
Mouse   534 LGVVFGPTLMRPQ-----------EETVAAIMDLKFQNIVVEILIENHEKIFRTSPDTTFAE 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	62/231 (27%)
Arhgap10	NP_084389.2	BAR	19..225	CDD:299863	26/162 (16%)
		BAR-PH_GRAF_family	267..372	CDD:269953	20/120 (17%)
		PH	269..367	CDD:278594	19/113 (17%)
		RhoGAP_Graf	367..569	CDD:239839	58/230 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	584..609		1/1 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	622..714
		SH3_GRAF2	732..785	CDD:212998

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910