Protein Alignment conu and arhgap18

DIOPT Version :9

• Sequence 1: NP_001036454.1
• Gene: conu / 3355133
• FlyBaseID: FBgn0039994
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001072336.1
• Gene: arhgap18 / 779789
• XenbaseID: XB-GENE-988160
• Length: 662
• Species: Xenopus tropicalis
• Alignment Length: 617
• Identity: 159/617 - (25%)
• Similarity: 266/617 - (43%)
• Gaps: 155/617 - (25%)

  Fly     2 NSNTDL-----HHSDDQDFSE--FLNEYYLQ-----------SNSQSIEPEASYEDGEMEAEWLV 48
            |.|..|     :.|..||..:  .|::|:.:           .:.|::..|.  ::||:|.|||.
 Frog    50 NVNPSLEKVAFNRSGSQDSLDELSLDDYWTEVENIKQDTNTSQDEQNVVKEP--DEGELEEEWLK 112

  Fly    49 SAGYPELTKPFEQGLEVSKKDLEPI--LTTLSKPHAEAIVQLVRTLNKTVRVRTKSRPKRKPDIR 111
            .||...|..      |.:....|.|  |:||:|..:.|:.:.:.|:.:|  :|.|:|..:.||:|
 Frog   113 EAGLSNLFN------ECAADPQESIVLLSTLTKTQSAAVQKRIDTVTQT--LRKKNRQHQIPDVR 169

  Fly   112 DVFREFDEQGTVTRSRSATPDSLDSLQIDEAWTNNSLPTFVNVYEKNTET--AIQCVEQSNEIYL 174
            |||::              |.:|.    |:|...|...:..:...||.|.  ..:||
 Frog   170 DVFKQ--------------PVNLQ----DKAGDINGFQSTESNDPKNEEANEKAECV-------- 208

  Fly   175 KQNLRRTPSAPPKSGTYADIFRGSQVRCDIPLYSADGVELLGYSRIGTIQFPRNRSVSDPFCSIG 239
                     ||..|....|         |:|:...| :.|       .|.|....|....|..:.
 Frog   209 ---------APEASRNVGD---------DLPVPVTD-INL-------EISFAEQASNLKDFTRVR 247

  Fly   240 RSKESRSENDARSQKKKSSEVLSASENECGRLLPMPYNVLSFESICRDSSSLDSCEVLDTCDIPS 304
            ..||..|                        |||      :|. :.:|.:..
 Frog   248 NEKEDDS------------------------LLP------NFR-LTQDKTGT------------- 268

  Fly   305 TLFTDVVLISETDMKRLQTILWLELATIFDRNKVSLDKRKPFKRRRKEEGNLFGVSINALIRRDQ 369
               |.:..::..|||::.::..:||..::|.....|..::..|.:.:|.| ||.|.::.|:.:||
 Frog   269 ---TKIGDLAPQDMKKVSSLALIELTALYDVLGTELKMQRAAKIKVRESG-LFRVPLSTLLDQDQ 329

  Fly   370 -QVTGTDSSLVPLFLEKLIGELLRRGSREEGLLRIGGHKQKTELLYNELESTFYQNPDNLDNLFR 433
             :..||   .|||..:.|||.:.:.|...||:|||.|...:.:.|..|||:.||:...|.||:.:
 Frog   330 KRAPGT---RVPLIFQSLIGHIEKGGLDTEGILRIPGASARIKALIEELEAKFYEGTFNWDNVKQ 391

  Fly   434 TATVHELSSLLKRWLRELPQPLLTNELIQLFYQCHTLPS-IDQMNALSILCHLLPPENRNTLRSL 497
                |:.:||||.::||||.||||.|.::.|:....||: ..::.||::|..|||..:|:||::|
 Frog   392 ----HDAASLLKFFIRELPLPLLTVEYLKAFHSVQYLPTKKHRLQALNLLVILLPEIHRDTLKAL 452

  Fly   498 LSFFNIIINLKDINKMNVHNVATIMAPSMFPPRYIHPSDNNSI----AEQVRMAAQCCRLTNILI 558
            |.|...:::.::.|||.:.|||.||||::|.   :|.....::    .|....||:...:...:|
 Frog   453 LEFLQRVVDHREQNKMILKNVAMIMAPNLFS---VHTYQLKTVDQGALEGAFSAARTASVMLFMI 514

  Fly   559 LRGEKLFQVPNNLIVE-------SQKTMMGKK 583
            .....|:.:|..::.:       :||.:..:|
 Frog   515 KYQNLLWTIPKFIVAQVRRQNIVNQKKLSKEK 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	77/232 (33%)
arhgap18	NP_001072336.1	RhoGAP_ARHGAP18	316..532	CDD:239856	77/225 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	108	1.000	Domainoid score	I6360
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	158	1.000	Inparanoid score	I4169
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D309300at33208
OrthoFinder	1	1.000	-	-		FOG0002326
OrthoInspector	1	1.000	-	-		otm49450
Panther	1	1.100	-	-	O	PTHR14963
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.070