DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment conu and Arhgap8

DIOPT Version :9

Sequence 1:	NP_001036454.1	Gene:	conu / 3355133	FlyBaseID:	FBgn0039994	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	XP_006521531.1	Gene:	Arhgap8 / 73167	MGIID:	1920417	Length:	480	Species:	Mus musculus

Alignment Length:	217	Identity:	64/217 - (29%)
Similarity:	100/217 - (46%)	Gaps:	36/217 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   357 FGVSINALIRRDQQVTGTDSSLVPLFLEKLIGELLRRGSREEGLLRIGGHKQ---KTELLYNELE 418
            ||||:..|..::|      ..|:|..|...:..|..:|.|.|||.|.....|   :.:.||::
Mouse   248 FGVSLQYLRDKNQ------GELIPPVLRWTVTYLREKGLRTEGLFRRSASAQTVRQVQRLYDQ-- 304

  Fly   419 STFYQNPDNLDNLFRTATVHELSSLLKRWLRELPQPLLTNELIQLFYQCHTLPSID---QMNALS 480
                ..|.|.|:.   ..:|..:.:||.:||||||||||   .|.:.|...:.|::   ::....
Mouse   305 ----GKPVNFDDY---GDMHLPAVILKTFLRELPQPLLT---FQAYEQILGITSVESSLRVTHCR 359

  Fly   481 ILCHLLPPENRNTLRSLLSFFNIIINLKDI-NKMNVHNVATIMAPSMFPPRYIHPSDN-NSIAEQ 543
            ::...||..|...||.|:.|.: .::|:.| ||||..|:|.:     |....|.||.. .|::..
Mouse   360 LILRSLPEHNYAVLRYLMGFLH-EVSLESISNKMNSSNLACV-----FGLNLIWPSQGVASLSAL 418

  Fly   544 VRMAAQCCRLTNILILRGEKLF 565
            |.:..    .|.:||...:|:|
Mouse   419 VPLNL----FTELLIEYYDKVF 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	64/217 (29%)
Arhgap8	XP_006521531.1	CRAL_TRIO_2	87..220	CDD:372686
Arhgap8	XP_006521531.1	RhoGAP	248..436	CDD:383032	63/215 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910