DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment conu and Arhgap19

DIOPT Version :9

Sequence 1:	NP_001036454.1	Gene:	conu / 3355133	FlyBaseID:	FBgn0039994	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	NP_081943.2	Gene:	Arhgap19 / 71085	MGIID:	1918335	Length:	494	Species:	Mus musculus

Alignment Length:	317	Identity:	85/317 - (26%)
Similarity:	140/317 - (44%)	Gaps:	81/317 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   306 LFTDVVLISETDMKRLQTILWLELATI-----------------FDRNKVSLDKRKPFKRRRKEE 353
            :||::|:   :::.||..:...|||.:                 |.|:.:||        :|||:
Mouse    56 VFTELVV---SNITRLIDLPGTELAQLMGEVDLKLPGGAGPAAGFFRSLMSL--------KRKEK 109

  Fly   354 GNLFGVSINALIRRDQQVTGTDSSLVPLFLEKLIGELLRRGSREEGLLRIGGHKQKTELLYNELE 418
            |.:||..:            |:..:..::  :|| |.|.:..|.|||.|:.|:..:.:||.:.|
Mouse   110 GVVFGSPL------------TEEGIAQIY--QLI-EYLHKNLRVEGLFRVPGNSVRQQLLRDAL- 158

  Fly   419 STFYQNPDNLDNLFRTATVH--ELSSLLKRWLRELPQPLLTNELIQLFYQCHTLPSID------- 474
                .|..::|  ..:...|  ::::|||.:|.|||:||||::...:..:...|...|
Mouse   159 ----NNGTDID--LDSGEFHSNDVATLLKMFLGELPEPLLTHKHFHVHLKIADLMQFDDKGNKTN 217

  Fly   475 ------QMNALSILCHLLPPENRNTLRSLLSFFNIIINLKDINKMNVHNVATIMAPSMFPPRYIH 533
                  |:.||.:|..:|||.|||.|:.||.........:|.|||:.||:|.:.||.:..|:.:.
Mouse   218 IPDKERQIEALQLLFLILPPANRNLLKLLLDLLYQTAKKQDKNKMSAHNLALMFAPHVLWPKNVT 282

  Fly   534 PSD--NNSIAEQVRMAAQCCRLTNILILRGEKLFQVP------NNLIVESQKTMMGK 582
            .:|  .|.|.....||        .:|...:|||:.|      ..|.....:|.|.|
Mouse   283 ANDLQENIIKLNTGMA--------FMIKHSQKLFKAPAYIRECARLYYLGSRTQMSK 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	66/242 (27%)
Arhgap19	NP_081943.2	RhoGAP_ARHGAP19	113..320	CDD:239857	65/236 (28%)
Arhgap19	NP_081943.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	399..451
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910