Protein Alignment conu and Dlc1

DIOPT Version :9

• Sequence 1: NP_001036454.1
• Gene: conu / 3355133
• FlyBaseID: FBgn0039994
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001357926.1
• Gene: Dlc1 / 58834
• RGDID: 68416
• Length: 1542
• Species: Rattus norvegicus
• Alignment Length: 975
• Identity: 185/975 - (18%)
• Similarity: 303/975 - (31%)
• Gaps: 419/975 - (42%)

  Fly     3 SNTDLHHSDDQDFSE------FLNEYYLQSNSQSIEPE-------------------ASYEDGEM 42
            :|...|..|.:..||      .:|:..:..:|:|.:|.                   |..|..|:
  Rat   401 TNLRRHVPDLESGSESGTESITVNQTQVNLSSESTDPSSTPASNSGTKPKAMAVPCIAEKETAEI 465

  Fly    43 EA----EWLVSAGYPELTKPFEQ-----GLEVSKKDLEPILTTLSKPHAEAIVQLVRTLNKTVRV 98
            ||    :||...|:|:..:.:|.     .:.:.|::.:    .|.:...||:.:.:.||||...:
  Rat   466 EAKEACDWLRVTGFPQYAQLYEDLLFPIDIALVKREHD----FLDRDAIEALCRRLNTLNKCAVM 526

  Fly    99 RTKSRPKRKPD-----------------IRDVFR-----EFDE--------QGTVTRSRSATPDS 133
            :.:..|.||..                 .||..|     |||.        .|:...||..:..|
  Rat   527 KLEISPHRKRSEDSDEEEPCAISGKWTFQRDSKRWSRLEEFDVFSPKQDPIPGSPDNSRLQSATS 591

  Fly   134 LDSLQID------------EAWTNNSLPTFV---------------------------------- 152
            .:|:..|            .:.|::|.||.|
  Rat   592 RESMLTDLSEHQEVSSIRSLSSTSSSAPTHVPHSGEATTPRTNSVISVCSSSHFVGNEDSFSSLP 656

  Fly   153 ------------NVYEKNTET-------------------------------------------- 161
                        ..:||||::
  Rat   657 SPKELSSFSFSMKGHEKNTKSKTRSLLKRMESLKLKGSHHSKHKAPSKLGLIISAPILQEGMDEE 721

  Fly   162 ---AIQCVEQS----NEIYLK-------QNLRRTPSAPPKSGTYADIFRGSQVRCDIPLYSAD-- 210
               .:.|||.|    |.|.:.       .|..:|.|:..:|.|.:.:...|.|.....|.:.:
  Rat   722 KLKQLNCVEISALNGNHINVPMVRKRSVSNSTQTSSSSSQSETSSAVSTPSPVTRTRSLSTCNKR 786

  Fly   211 -GVELLGYS---------------------------------RIGTIQFPRNRSVSDPFCSIGRS 241
             |:.|.|:.                                 :.||  ||:..| :..||..|.|
  Rat   787 VGMYLEGFDPFSQSAFNNVTEQNYKNRESYPEDTVFYIPEDHKPGT--FPKALS-NGSFCPSGNS 848

  Fly   242 KES--------------RSENDARSQKK-----KSSEV---LSASENECGRLL------------ 272
            ..:              |.||.:.|.|:     .||.|   :|..:|..|.:|
  Rat   849 SVNWRTGSFHGPGHLSLRRENSSDSPKELKRRNSSSSVSSRMSIYDNVPGSILYSSSGELADLEN 913

  Fly   273 --------PMPYNVLSFESI-----------------------C---------------RDSSSL 291
                    .:.|:|...:.|                       |               |..|.|
  Rat   914 EDIFPELDDILYHVKGMQRIVNQWSEKFSDEGDSDSALDSVSPCPSSPKQIHLDVDHDRRTPSDL 978

  Fly   292 DSC-----EVLDTCDIP--------------------------------STLFTDVVLISETDMK 319
            ||.     |..:..|||                                :::...:...|...|.
  Rat   979 DSTGNSLNEPEEPTDIPERRDSGVGASLTRCNRHRLRWHSFQSSHRPSLNSVSLQINCQSVAQMN 1043

  Fly   320 RLQTILWLELATIFDR----NKVSLDKRKP-FKRRRK----EEGNLFGVSINALIRRDQQVTGTD 375
            .||....|:|..:.::    ||.......| |.:|.|    ::.::|||.:...::|..|.
  Rat  1044 LLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRSGQP---- 1104

  Fly   376 SSLVPLFLEKLIGELLRRGSREEGLLRIGGHKQKTELLYNELEST-FYQNPDNLDNLFRTATVHE 439
               :|..:::.:..|......:.||.|..|.|.:.:.|....||. .|.|       :...:.::
  Rat  1105 ---LPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNESAEDYVN-------YEGQSAYD 1159

  Fly   440 LSSLLKRWLRELPQPLLTNELIQLFYQCHT-LPSIDQMNALSILCHLLPPENRNTLRSLLSFFNI 503
            ::.:||::.|:||:||:||:|.:.|.|.:. :|...::.|:.....|||.|||..|::||.|.:.
  Rat  1160 VADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSD 1224

  Fly   504 IINLKDINKMNVHNVATIMAPSMF----------PPRYIHPS-----------DNNSIAEQ--VR 545
            :......|:|...|:|..:|||:|          .||.:...           :.|..|.|  ..
  Rat  1225 VTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAH 1289

  Fly   546 MAAQCCRLTNILILRGEKLFQVPNNLIVESQKTMMGKKGWHRHRNS------NEITAKPSGKASN 604
            |.|:|           :||||||..:              .|.|||      ..:|.:..|..||
  Rat  1290 MIAEC-----------KKLFQVPEEM--------------SRCRNSYTEQELKPLTLEALGHLSN 1329

  Fly   605  604
              Rat  1330  1329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	63/244 (26%)
Dlc1	NP_001357926.1	SAM_DLC1	468..527	CDD:188990	13/62 (21%)
		RhoGAP_DLC1	1086..1304	CDD:239840	63/242 (26%)
		SRPBCC	1329..1532	CDD:417480	1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810