Protein Alignment conu and RhoGAP1A

DIOPT Version :9

• Sequence 1: NP_001036454.1
• Gene: conu / 3355133
• FlyBaseID: FBgn0039994
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001284725.1
• Gene: RhoGAP1A / 5740235
• FlyBaseID: FBgn0025836
• Length: 1404
• Species: Drosophila melanogaster
• Alignment Length: 803
• Identity: 147/803 - (18%)
• Similarity: 255/803 - (31%)
• Gaps: 311/803 - (38%)

  Fly    24 LQSNSQSIEPEASYEDGEMEAEWLVSAGYPELTKPFEQGLEVSKKDLE--------PILTTLS-- 78
            |.:...||.|..:..|.|....   ::.|..:....:||:|.....|:        |||.|:|
  Fly   580 LSTPGSSILPLPNVADPESPGR---TSNYVNIDFFLQQGIETRSSSLDSDGEYEGPPILRTISHD 641

  Fly    79 -------KPHA------------------------EAIVQ----LVRTLNKTVRVR-------TK 101
                   .|.|                        .:|:|    .|..|||.::.:       |.
  Fly   642 DQTTTQTTPGAIRKNLVSAILVCGNARGAKIRSILSSIIQSETIYVECLNKMMQYKKAIHATLTT 706

  Fly   102 SRPK-RKPDIRDVFREFDE-----QGTVTRSRSATPDSLDSLQIDEAWTN-----NSLPTFVNVY 155
            |:|. |:.:...:|.:.||     .|.::..::........:.|.|.:..     :....|::.|
  Fly   707 SQPVIREEEENTIFFKIDELYDLHTGFLSDLKTIVSHEGGDVLIGEPFRRLAEMFDLYSAFLHNY 771

  Fly   156 EKNTETAIQC-------------------VEQS----------------NEIYLKQNLRRTPSAP 185
            :...||..:|                   .|||                |.:.....||.||:|.
  Fly   772 KNAIETVKKCSANNPQFKKIVSTIVLNLQTEQSLTLEDLLHKPVARVQINALVFNDLLRETPNAH 836

  Fly   186 P--------------------------------------KSGTYADIFRGSQ-----------VR 201
            |                                      ::....::..|.:           :.
  Fly   837 PDHQPLRQAQKIIQMFLNQFNVVNQRLPIESNRNLRRMVRNSFIVELVDGHRKLRHLFLFNDVIA 901

  Fly   202 C----------------------DIPLY-SAD-GVELLGYSRIGTIQFPRN-RSVSDPFC-SIGR 240
            |                      |:.:| .|| .|||...|.....|..|| |||.|... .:..
  Fly   902 CAKYKALGRDRIDYELKWFIPLKDVSIYEEADPAVELKESSPANISQVKRNLRSVRDQLAMEVAN 966

  Fly   241 SKESRSENDARSQKKKS---SEVLSASENECGRLLPMPYN-------------------VLSFES 283
            |......:..:.::|.:   |:::.|:.|...||.....|                   :||.:.
  Fly   967 SGSGAFRSGDKYRRKLADLESQLVLATPNLVLRLGNKANNKTITFFLSSDFERTQWIDSILSLKQ 1031

  Fly   284 ICR--DSSSLDSCEVL-----------------------DTCDIPSTLF------------TDVV 311
            .|.  .:::::|.||.                       |...:...|:            .|:.
  Fly  1032 KCNLPGANTINSLEVTAFIVAMQKGMKTEMGSYLMRNTNDESLLVGDLYMGVHGLEGLEQANDLY 1096

  Fly   312 LISETD-------------MKRLQTILW-----LEL-------ATIFDRNKVSLDKRK------- 344
            :..|.|             :.|.||.||     |||       ..:::..:..|.|.|
  Fly  1097 ICVEVDSYGHYFRKATTKKICRSQTPLWNESFMLELEGSQNVRILLYEAKERPLLKAKHILKLSL 1161

  Fly   345 ----------------------PFK-------RRRKEEGNLFGVSINALIRRDQQVTGTDSSLVP 380
                                  .|:       |...:.|.|||..::.:::|:::.       :|
  Fly  1162 SWLTETTQPKSIKLTETLELGCSFRFIPGELFRGSTKPGALFGAKMSQVLKREKRD-------IP 1219

  Fly   381 LFLEKLIGELLRRGSREEGLLRIGGHKQKTELLYNELESTFYQNPDNLDNLFRTATVHELSSLLK 445
            ..:...|.|:.|||..|.|..|:.|.......|....||..|:    .:.|.|...:|.::.:||
  Fly  1220 FIIGACIREVERRGMLEVGCYRVSGSASDLAKLKKAFESDAYE----AEQLLREVDIHSVTGILK 1280

  Fly   446 RWLRELPQPLLTNELIQLFYQCHTLPSID----QMNALSILCHLLPPENRNTLRSLLSFFNIIIN 506
            .:|||||:.|.|::|...|:...:..|.:    ::|.|..:...||..|:.::.|:|.....:..
  Fly  1281 TFLRELPEALFTDQLYPRFFDTFSAFSNNNESTRINELLKVFEELPQANKASITSILDHLIRVHE 1345

  Fly   507 LKDINKMNVHNVATIMAPSMFPP 529
            .:..|||::||:|.:..|::..|
  Fly  1346 KETDNKMSLHNLAMVFGPTLLRP 1368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	48/178 (27%)
RhoGAP1A	NP_001284725.1	RhoGEF	675..857	CDD:214619	31/181 (17%)
		PH_BCR_arthropod	851..1037	CDD:270174	28/185 (15%)
		C2	1079..1187	CDD:301316	16/107 (15%)
		RhoGAP	1203..1398	CDD:295372	47/177 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910