Protein Alignment conu and arhgap12a

DIOPT Version :9

• Sequence 1: NP_001036454.1
• Gene: conu / 3355133
• FlyBaseID: FBgn0039994
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_021336423.1
• Gene: arhgap12a / 563267
• ZFINID: ZDB-GENE-050809-38
• Length: 853
• Species: Danio rerio
• Alignment Length: 595
• Identity: 121/595 - (20%)
• Similarity: 220/595 - (36%)
• Gaps: 147/595 - (24%)

  Fly     7 LHHSDDQDFSEFLNEYYLQSNSQSIEPEASYEDGEMEAEW-LVSAGY-------PELTKPFEQGL 63
            |.|:|::.     ..||..:            ||. .:|| |...|.       |.:.....:..
Zfish   343 LRHTDERG-----RLYYYSA------------DGS-RSEWELPKIGLKSQSNHTPLMPGDLHKTR 389

  Fly    64 EVSKKDLEPILTTLSKPHA----EAIVQLVRTLNKTVRVRTKSRPKRKPDIRDVFREFDEQGTVT 124
            .:.::..:||..:.::.|:    |...:|.:   |.|:||....|:||..:|.  ..:..|.|.|
Zfish   390 SLDRRLPDPIPISRTQRHSIYSHETNDKLKQ---KFVKVRQSFLPRRKTTLRS--HPYFPQDTKT 449

  Fly   125 RSRSATPDSLDSLQIDEAWTNNSLPTFVNVYEKNTETAIQCVEQSNEIYLKQNLRRTPSAPPKSG 189
            .|    |||      |.:..::..|......:..|....:..|...::  ::|..
Zfish   450 GS----PDS------DSSCPSSPKPPHSPSEKCATLNMTKITEHGKKV--RKNWT---------- 492

  Fly   190 TYADIFRGSQVRCDIPLYS---ADGVELLGYSRIGTIQFP---RNRSVSDPFCSIGRSKESRSEN 248
            :|..:.:||     :.:::   ..|....|..:..::::.   :..||.      ..||:..|:.
Zfish   493 SYWTVLQGS-----LLIFNKGQGGGSGWFGRDQKSSVEYSVDLKGGSVD------WASKDKSSKK 546

  Fly   249 DARSQK-KKSSEVLSASE-----NECGRLLPMPYNVLSFESICRDSSSLDSCEVLDTCDIPSTLF 307
            .....| ::.:|:|..|:     |:..:.|....:...:||        |.....|..:.|....
Zfish   547 HVLELKTRQGTELLLQSDSDGLVNDWHKALTEAIHTYMWES--------DEAIEEDMPESPENEK 603

  Fly   308 TDVVLISETDMKRLQTILWLELATIFD------RNK-VSLDKRKPFKRRRKEEG----NLFGVSI 361
            .|    .|.|.|..:....::.....|      :|| |.|...:|..:..|::|    .:||.|:
Zfish   604 HD----KEKDRKNSKKARDIKKTASMDNAEQKKKNKLVVLLLGRPTLQAVKDKGYIKDQVFGCSL 664

  Fly   362 NALIRRDQQVTGTDSSLVPLFLEKLIGELLRRGSREEGLLRIGG-------------HKQKTELL 413
            ::|.:|       ::|.||.|:...|.::.:.|...:||.|:.|             |::|.:|.
Zfish   665 SSLCQR-------ENSTVPRFVWLCIEQVEKNGLGVDGLYRVSGNLAIIQKLRFAVNHEEKIDLG 722

  Fly   414 YNELESTFYQNPDNLDNLFRTATVHELSSLLKRWLRELPQPLLTNELIQLFYQCHTLPSIDQ-MN 477
            .::.|.                 :|..:..||.:.||||:||.|......|.....:|...| :.
Zfish   723 DSKWED-----------------IHVTTGALKMFFRELPEPLFTYTFFSDFISAIKMPDYKQKVQ 770

  Fly   478 ALSILCHLLPPENRNTLRSLLSFFNIIINLKDINKMNVHNVATIMAPSMFPPRY------IHPSD 536
            .:..|...||..|.:|::.|......:|...|.|:|...:||.:..|::..|..      :|...
Zfish   771 TVKDLMKKLPRPNHDTIQVLFKHLKKVIQHVDENRMTTQSVAIVFGPTLLRPEIETANMAVHMVY 835

  Fly   537 NNSIAEQVRM 546
            .|.|.|.:.|
Zfish   836 QNQIVELILM 845

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	51/211 (24%)
arhgap12a	XP_021336423.1	SH3_ARHGAP12	11..70	CDD:213003
		SH3-WW_linker	67..233	CDD:318759
		WW	252..278	CDD:306827
		PH_ARHGAP9-like	470..580	CDD:270053	19/132 (14%)
		RhoGAP_ARHGAP27_15_12_9	660..846	CDD:239868	51/210 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910