Protein Alignment conu and si:dkey-91m11.5

DIOPT Version :9

• Sequence 1: NP_001036454.1
• Gene: conu / 3355133
• FlyBaseID: FBgn0039994
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_021333943.1
• Gene: si:dkey-91m11.5 / 560226
• ZFINID: ZDB-GENE-060503-932
• Length: 1312
• Species: Danio rerio
• Alignment Length: 847
• Identity: 164/847 - (19%)
• Similarity: 269/847 - (31%)
• Gaps: 339/847 - (40%)

  Fly     2 NSNTDLHHSDDQDFSEFLNEYYL----QSNSQSIEPE-ASYEDGEMEAEWL----------VSAG 51
            |.:...|...|..||......|:    :.:.|.::.: .||.|..:.:..|          .|:|
Zfish   444 NFSNSFHGDLDIPFSGTPPPAYVYDGDRGDDQRLQSDIVSYSDDPLFSPRLHPKGRSIRETPSSG 508

  Fly    52 YPELTK----PFEQGLEVSKKDLEPILTT----LSKPHAEAIVQLVRTLNKTVRVRTKSRPK--- 105
            .||.||    ..|:|||:.|..|..||.:    ||  |.||::..::.|....   |.|:|.
Zfish   509 SPESTKSSELDAEKGLEMRKWVLSGILASEEAYLS--HLEALLVPMKPLKAAA---TTSQPMLTL 568

  Fly   106 --------RKPDIRDVFREFDEQGTVTR-----SRSATPDSLDSLQIDEAWTNNSLPTFVNVYEK 157
                    ..|::.::.::|.: |.:.|     :|....|....|    |........||:.|:.
Zfish   569 QQIETIFFNVPELHEIHKDFYD-GLLPRVQQWSNRQCVGDLFQKL----ASQLGVYRAFVDNYKI 628

  Fly   158 NTETAIQCVEQSNE-------------------------------------IYLKQNLRRTPSAP 185
            ..|||.:|.:.:::                                     :.|...|:.|||:.
Zfish   629 AVETAEKCCQANSQFAEISENLKVKSAKDQNAKHSLETLLYKPVDRVTRSTLVLHDLLKHTPSSH 693

  Fly   186 PKSGTYADIFRGSQ---------------------------VRCDIPLYSADGVELL-------- 215
            |......|..|.||                           :|....:...:|...|
Zfish   694 PDYPLLQDALRISQNFLSSINEEITPRRQSMTVKKGENRQLLRDQFMVELVEGARKLRHVFLFTD 758

  Fly   216 ---------------------GYSRIGTIQFPR-NRSVSDPFCSIG-------RSKESRSENDAR 251
                                 .|..:..:.|.. :.|.|.|...|.       :.|.|:.:|:.:
Zfish   759 ILLCAKLKKQTGGKGQQYDCKWYIPLADVTFQTIDESESSPVPQIPEEEIDALKVKISQIKNEIQ 823

  Fly   252 SQKK--KSSEVL-----SASENECGRLLPMP-------------YNVL----------------- 279
            .:|:  |..:||     ...|.|...||..|             |..|
Zfish   824 REKRVCKGGKVLDRLRKKLCEQESLLLLMSPCMAFRVSNRNGKGYTFLISSDYEREEWREVIREQ 888

  Fly   280 ---SFESICRDSSSL----DSCEVLDTC-DIPSTL------------------------------ 306
               .|:|....|..|    :||..|.|. .||.|:
Zfish   889 QKKCFKSFSLTSLELQMLTNSCVKLQTVHSIPLTVNKDGACLIFLFCFALFCPLTVNKDDDESTG 953

  Fly   307 ---FTDVVLISETDMKR-------------------------------------------LQTIL 325
               |.:|::.|.|.:|:                                           .||:.
Zfish   954 LCGFLNVIVHSATGLKQSLNLYCTLEVDSFGYFVNKAKTRVYRDTTEPNWNEEFEIELEGSQTLR 1018

  Fly   326 WL-------------ELATIFDRNKVSLD----------------------------------KR 343
            .|             .:..:..:.::.||                                  ||
Zfish  1019 LLCYSKIKQCRDDGENIDRVMAKGQIQLDPQSLQGKDWQRTVISMNGIEVKLSMRFTSREFSLKR 1083

  Fly   344 KPFKRRRKEEGNLFGVSINALIRRDQQVTGTDSSLVPLFLEKLIGELLRRGSREEGLLRIGGHKQ 408
            .|   .||:.| :|||.|.|:.:|:.       |.|||.:.:.:.|:.|||..|.|:.|:.|  .
Zfish  1084 MP---SRKQSG-VFGVKIGAVTKREH-------SKVPLIVRQCVEEIERRGMEEVGIYRVSG--V 1135

  Fly   409 KTELLYNELESTFYQNPDNLDNLFRTATVHELSSLLKRWLRELPQPLLTNELIQLFYQCHTL-PS 472
            .|::  ..|::.|..|..::..:.....|:.::..||.:.||||:||.|:||...|.:...| .|
Zfish  1136 ATDI--QALKAAFDANNKDVSVIMSEMDVNAIAGTLKLYFRELPEPLFTDELYINFTEGIALSDS 1198

  Fly   473 IDQMNALSILCHLLPPENRNTLRSLLSFFNIIINLKDINKMNVHNVATIMAPSMFPPRYIHPSDN 537
            :.:.:.:..|...||..|..|...||.....:...:.:|||:.||:||:..|::     :.||:.
Zfish  1199 VAKESCMLNLLLSLPEPNLLTFLFLLDHLKRVAENEIVNKMSFHNLATVFGPTL-----LRPSEK 1258

  Fly   538 NS 539
            :|
Zfish  1259 DS 1260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	55/185 (30%)
si:dkey-91m11.5	XP_021333943.1	Bcr-Abl_Oligo	3..75	CDD:312543
		RhoGEF	527..714	CDD:238091	38/196 (19%)
		PH_BCR_vertebrate	709..901	CDD:270173	25/191 (13%)
		C2_ABR	958..1074	CDD:176068	9/115 (8%)
		RhoGAP_Bcr	1093..1293	CDD:239852	55/184 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910