DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment conu and arhgap17

DIOPT Version :9

Sequence 1:	NP_001036454.1	Gene:	conu / 3355133	FlyBaseID:	FBgn0039994	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	XP_002932512.1	Gene:	arhgap17 / 549590	XenbaseID:	XB-GENE-981776	Length:	856	Species:	Xenopus tropicalis

Alignment Length:	218	Identity:	61/218 - (27%)
Similarity:	102/218 - (46%)	Gaps:	34/218 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   327 LELATIFDRNKV-SLDKRKPFKRRRKE---EGNLFGVSINALIRRDQQVTGTDSSLVPLFLEKLI 387
            ||....:.|..: :|:|..|..:.:::   |...||..:...::|    :|.:   :.|.:|..:
Frog   216 LETQAEYHRKALAALEKALPEIQAQQDKWTEKPAFGTPLEEHLKR----SGRE---IALPIEACV 273

  Fly   388 GELLRRGSREEGLLRIGGHKQKTELLYNELEST------FYQNPDNLDNLFRTATVHELSSLLKR 446
            ..||..|.:||||.||.....|.:.|...|:.:      ||.:|            |.::..||.
Frog   274 MMLLETGMKEEGLFRIAAGASKLKKLKAALDCSTSQLEEFYSDP------------HAVAGALKS 326

  Fly   447 WLRELPQPLLTNELIQLFYQCHTLPSIDQ---MNALSILCHLLPPENRNTLRSLLSFFNIIINLK 508
            :|||||:||:|..|.:.:.....:|  ||   :.||.::|..||..|....|.|:.|...:.:..
Frog   327 YLRELPEPLMTFNLYEEWNHAGNIP--DQNTKLQALWVVCQKLPKPNLENFRYLVKFLAKLSHHS 389

  Fly   509 DINKMNVHNVATIMAPSMFPPRY 531
            |||||...|:|.::.|::...|:
Frog   390 DINKMTPSNIAIVLGPNLLWARH 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	54/185 (29%)
arhgap17	XP_002932512.1	BAR	13..257	CDD:386243	9/40 (23%)
		RhoGAP_nadrin	246..445	CDD:239851	55/188 (29%)
		DUF5585	515..>849	CDD:375359
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910