Protein Alignment conu and Arhgap40

DIOPT Version :9

• Sequence 1: NP_001036454.1
• Gene: conu / 3355133
• FlyBaseID: FBgn0039994
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001138487.1
• Gene: Arhgap40 / 545481
• MGIID: 3649852
• Length: 672
• Species: Mus musculus
• Alignment Length: 654
• Identity: 156/654 - (23%)
• Similarity: 252/654 - (38%)
• Gaps: 175/654 - (26%)

  Fly    13 QDFSEFLNEYYLQSNSQSIEPEASYEDGEMEAEWLVSAGYPELTKPFEQGLEVSKKDLEPILTTL 77
            |..:|...|...:..||.:|       |:.|::||...|...|....  ||:   .|.:.:|:||
Mouse    91 QQRAEVKKEDCGEGRSQLLE-------GDTESQWLQDTGLSGLAGGL--GLD---GDHQGLLSTL 143

  Fly    78 SKPHAEAIVQLVRTLNKTVRVRTKSRPKRKPDIRDVFREFDEQGTVTRSRSATPDSLDSLQIDEA 142
            ::....|:.:.:....::.|.|.|: |.|  |:||:|      |..|....|..:.:..::
Mouse   144 TQTQVAAVCRRLDIYARSARRRQKA-PVR--DVRDIF------GVFTSRELAPENGVSGMK---- 195

  Fly   143 WTNNSLPTFVNVYEKNTETAIQCVEQSNEIYLKQNLRRTPSAPPKSGTYADIFRGSQVRCDIPLY 207
            ||        .:..:::.:.::..|              |..|.:.....::|.....      |
Mouse   196 WT--------KINSEDSASPLRSAE--------------PGGPQELAGMEEVFNMDSA------Y 232

  Fly   208 SADGVELL--------GYSRIGTIQFPRNRSVSDPFCSIGRSKESRSENDARSQKKKSSEVLSAS 264
            |.....||        |.:..|....||.|...
Mouse   233 SEQAAVLLQRAWPSPGGTTAWGKGPLPRFRIPK-------------------------------- 265

  Fly   265 ENECGRLLPMPYNVLSFESICRDSSSLDSCEVLDTCDIPSTLFTDVVLISETDMKRLQTILWLEL 329
                |||           .:.|...                       :|..|||::..:..:||
Mouse   266 ----GRL-----------GVTRIGD-----------------------LSSRDMKKIPPLALIEL 292

  Fly   330 ATIFDRNKVSLDKRKPFKRRRKEEGNLFGVSINALIRRDQQVTGTDSSLVPLFLEKLIGELLRRG 394
            ..::|...:.|.:.|..|.:..:.| ||||.:::|:..|.:|  ..|:.|||.|:.|:..|.:||
Mouse   293 TALYDILGLDLKRCKGGKWKGPDSG-LFGVPLHSLLEADHRV--FPSTQVPLLLQALLSCLEKRG 354

  Fly   395 SREEGLLRIGGHKQKTELLYNELESTFYQNPDNLDNLFRTATVH--ELSSLLKRWLRELPQPLLT 457
            ...||:||:.|.:.:.:.|..:||..||....:.|.      ||  :.|.||||:||:||.||||
Mouse   355 LDTEGILRVPGSQARVKGLEQKLERDFYAGLVSWDK------VHPNDASDLLKRFLRKLPVPLLT 413

  Fly   458 NELIQLFYQCHTLPSIDQ-MNALSILCHLLPPENRNTLRSLLSFFNIIINLKDINKMNVHNVATI 521
            .|.:..|.....:|.:.| :.||.:|..|||..|||||::||.|...:...:..|||.:.||:|:
Mouse   414 AEYLPAFASVPDIPDLKQRLQALHLLVLLLPEPNRNTLKALLEFLRKVAAQEQHNKMTLWNVSTV 478

  Fly   522 MAPSMFPPRYIHPSDNNSIAEQVRMAAQCCRLTNILILRGEKLFQVPNNLIVE-----------S 575
            |.||:|.||...|.......:....||:   :..:::...:.|:.|.:.|:.:           |
Mouse   479 MVPSLFLPRGRPPKLTKGGKQLAEGAAE---VVCMMVQYQDLLWTVASFLVAQVRKLNDSNGRRS 540

  Fly   576 QKTMMGKKGW----HRHRNSN----EITAK----------PSGKASNVGVGHDSTVINKYSTNLK 622
            |....|.|.|    |..|:..    |.|.|          ||.....|.:...:.|.:......:
Mouse   541 QLCDGGLKTWLWRTHVDRDKAGEGLEATPKVAKIQVQATWPSMDLLQVPLNPSTRVTHVLKLFTE 605

  Fly   623 HLHP 626
            ||:|
Mouse   606 HLNP 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	78/233 (33%)
Arhgap40	NP_001138487.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	43..68
		RhoGAP	318..530	CDD:295372	78/222 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838665
Domainoid	1	1.000	110	1.000	Domainoid score	I6305
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	187	1.000	Inparanoid score	I3900
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002326
OrthoInspector	1	1.000	-	-		otm44275
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14963
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.990