Protein Alignment conu and Arhgap27

DIOPT Version :9

• Sequence 1: NP_001036454.1
• Gene: conu / 3355133
• FlyBaseID: FBgn0039994
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001192165.1
• Gene: Arhgap27 / 544817
• MGIID: 1916903
• Length: 869
• Species: Mus musculus
• Alignment Length: 527
• Identity: 111/527 - (21%)
• Similarity: 198/527 - (37%)
• Gaps: 115/527 - (21%)

  Fly    16 SEFLNEYYLQSNSQSIEPEASYEDGEMEAEWLVSAGYPELTKPFEQGLEVSKKDLEPILTTLSKP 80
            ::|..|.:::...|..:| ..|...:...:|.:    |::..|..:.:..|.:|.:      :..
Mouse   413 NQFTQEQWVRLEDQHGKP-YFYNPEDSSVQWEL----PQVPIPAPRSVRKSSQDSD------TPA 466

  Fly    81 HAEAIVQLVRTLNKT-VRVRTKSRPKRKPDIRDVFREFDEQGTVTRSRSATPDSLDSLQIDEAWT 144
            .|....:.::||:|. |..|||:..|.|                         .|.......:||
Mouse   467 QASPPEEKIKTLDKAGVLHRTKTVDKGK-------------------------RLRKKHWSTSWT 506

  Fly   145 NNSLPTFVNVYEKNTETAI-----QCVEQSNEIYLKQNLRRTPSAPPKSGTYADIFRGSQVRCDI 204
              .|...|..:.|:::|:.     |..:.|...|..:....:.|..||.        .|..:..:
Mouse   507 --VLEGGVLTFFKDSKTSAAGGLRQPSKLSTPEYTVELKGASLSWAPKD--------KSSKKNVL 561

  Fly   205 PLYSADGVELLGYSRIGTIQFPRNRSVSDPFCSIGRSKESRSENDARSQKKKSSEVLSASENECG 269
            .|.|.||.|.|.......|....::::::....:........|.:..|....|||.|.:...|..
Mouse   562 ELRSRDGSEYLIQHDSEAIISTWHKAIAEGISELSADLLQGEEGEPSSADFGSSERLGSWREEDV 626

  Fly   270 RLLPMPYNVLSFESICRDSSSLDSCEVLDTCDIPSTLFTDVVLISETDMKRLQTILWLELATIFD 334
            |           ::....|.|            |..|        |:|:.|:
Mouse   627 R-----------QNAASPSLS------------PGGL--------ESDLSRV------------- 647

  Fly   335 RNKV-SLDKRKPFKRRRKEEG----NLFGVSINALIRRDQQVTGTDSSLVPLFLEKLIGELLRRG 394
            |:|: ...:|:|..:..:::|    .:||.::..|..|::       |.||.|:::.|..:..||
Mouse   648 RHKLRKFLQRRPTLQSLRDKGYIKDQVFGCALAQLCERER-------SPVPRFVQQCIRTVEARG 705

  Fly   395 SREEGLLRIGGHKQKTELLYNELESTFYQNPDNLD-NLFRTATVHELSSLLKRWLRELPQPLLTN 458
            ...:||.||.|:....:.|..:::     :.:.|| :..|...||.::..||.:.||||:||...
Mouse   706 LDIDGLYRISGNLATIQKLRYKVD-----HDERLDLDDGRWEDVHVITGALKLFFRELPEPLFPF 765

  Fly   459 ELIQLFYQCHTLPSIDQMN-ALSILCHLLPPENRNTLRSLLSFFNIIINLKDINKMNVHNVATIM 522
            .....|.....|....|.: .:..|...||..|::|||.|:.....:|...:.|:|.|.|||.:.
Mouse   766 SHFHQFIAAIKLQDPAQRSRCVRDLVRTLPAPNQDTLRLLIQHLCRVIEHGEQNRMTVQNVAIVF 830

  Fly   523 APSMFPP 529
            .|::..|
Mouse   831 GPTLLRP 837

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	50/176 (28%)
Arhgap27	NP_001192165.1	SH3_ARHGAP27	10..66	CDD:213002
		PRK12323	<68..249	CDD:237057
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	104..134
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	208..300
		PRP40	241..>328	CDD:227435
		WW	248..278	CDD:395320
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	331..401
		WW	418..445	CDD:395320	5/31 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	443..477		5/43 (12%)
		PH_ARHGAP9-like	480..594	CDD:270053	28/148 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	623..642		6/49 (12%)
		RhoGAP_ARHGAP27_15_12_9	675..861	CDD:239868	50/175 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910