DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment conu and Arhgap30

DIOPT Version :9

Sequence 1:	NP_001036454.1	Gene:	conu / 3355133	FlyBaseID:	FBgn0039994	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	NP_001102547.1	Gene:	Arhgap30 / 498282	RGDID:	1561419	Length:	1104	Species:	Rattus norvegicus

Alignment Length:	232	Identity:	58/232 - (25%)
Similarity:	101/232 - (43%)	Gaps:	19/232 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   340 LDKRKPFKRRRKEEGNLFGVSINALIRRDQQVTGTDSSLVPLFLEKLIGELLRRGSREEGLLRIG 404
            :..|:..|::...:..:||..    :|...|.:|.:   ||..| :...|.::.....:|:.|:.
  Rat     1 MKSRQKGKKKGSSKERVFGCD----LREHLQQSGQE---VPQVL-RSCAEFVQEYGVVDGIYRLS 57

  Fly   405 GHKQKTELLYNELESTFYQNPDNLDNLFRTATVHELSSLLKRWLRELPQPLLTNELIQLFYQCHT 469
            |.....:.|..|.|:.  :.||...::: ...:|.:|||.|.:.||||.||||..|...|.:...
  Rat    58 GVSSNIQKLRQEFEAE--RKPDLRRDVY-LQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVA 119

  Fly   470 LPSIDQMNALSILCHL--LPPENRNTLRSLLSFFNIIINLKDINKMNVHNVATIMAPSMFPPRYI 532
            : .::....:.||..|  ||..|..||..|:.....:.:......|:..|:|.:.||::...:.|
  Rat   120 V-QLEPERLVKILEVLQELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNLLRSKDI 183

  Fly   533 HPSDNNSIAEQVRMAAQCCRLTNIL-----ILRGEKL 564
            ..|..|..|..:.:..|...:..||     :.||:.|
  Rat   184 EASGFNGTAAFMEVRVQSIVVEFILTHVDQLFRGDSL 220

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	56/216 (26%)
Arhgap30	NP_001102547.1	RhoGAP_CdGAP	16..210	CDD:239849	53/205 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910