DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment conu and Stard13

DIOPT Version :9

Sequence 1:	NP_001036454.1	Gene:	conu / 3355133	FlyBaseID:	FBgn0039994	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	XP_006248805.1	Gene:	Stard13 / 498130	RGDID:	1564816	Length:	1131	Species:	Rattus norvegicus

Alignment Length:	443	Identity:	101/443 - (22%)
Similarity:	181/443 - (40%)	Gaps:	83/443 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   222 TIQFPRNRSVSD----PFCSIGRSKESRSENDARSQKKKSSEVLSASENECGRLLPMPYNVLSFE 282
            |:.|..| |||:    | ..:.|.:.|.:|:|....:::....:.||.....|.|......||.:
  Rat   532 TLDFEGN-SVSEGQTTP-SDVERDRTSLNESDTTGVRERRDSGVGASLTRPNRRLRWSSFQLSHQ 594

  Fly   283 SICRDSSSLDSCEVLDTCDIPSTLFTDVVLISETDMKRLQTIL----------WLELA------T 331
            .....:          |..|.|.....:.|:....:.||..|:          |..|:      .
  Rat   595 PQLSPA----------TPHISSQTAAQLNLLQRFSLLRLTAIMEKYSMSNKHGWTCLSAQSAPGA 649

  Fly   332 IFDRNKVSLDKRKPFKRRRK----EEGNLFGVSINALIRRDQQVTGTDSSLVPLFLEKLIGELLR 392
            :.|...|:......|.:|.|    .:..:|||.:...::|..|.       :|..:::.:..|..
  Rat   650 LHDLVSVNSRSVPKFMKRIKAPDYRDKAVFGVPLIVHVQRTGQP-------LPQSIQQALRYLRS 707

  Fly   393 RGSREEGLLRIGGHKQKTELLYNELESTFYQNPDNLDNLFRTATVHELSSLLKRWLRELPQPLLT 457
            ....:.||.|..|.|.:...| .::...|   |||:.  :...:.::::.::|::.|:||:||.|
  Rat   708 NCLDQVGLFRKSGVKSRIHAL-RQMNENF---PDNVS--YEDQSAYDVADMVKQFFRDLPEPLFT 766

  Fly   458 NELIQLFYQCHT-LPSIDQMNALSILCHLLPPENRNTLRSLLSFFNIIINLKDINKMNVHNVATI 521
            |:|.:.|...:. :|...::.|:.....||..|||..|::||.|.:.::||.|.|:|...|:|..
  Rat   767 NKLSETFLHIYQYVPKEQRLQAVQAAILLLADENREALQTLLCFLHDVVNLVDENQMTPMNLAVC 831

  Fly   522 MAPSMF---------PPRYIHPS------DNNSIAEQVRMAAQCCRLTNILILRGEKLFQVPNNL 571
            :|||:|         .||.|...      |...:.|.:..|.....    :|....:||:||:.:
  Rat   832 LAPSLFHLNLLKKESSPRVIQKKYATGKPDQKDLNENLAAAQGLAH----MITECNRLFEVPHEM 892

  Fly   572 IVESQKTMMGKKGWHRHRNSNEITAKPSGKASNVGVGHDSTVINKYSTNLKHL 624
            :.:|:.:.:          ..||.| ||.:.....:..:....:.|   |:||
  Rat   893 VAQSRNSYL----------EAEIHA-PSLEDLGTQLAENGATFHTY---LEHL 931

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	60/235 (26%)
Stard13	XP_006248805.1	SAM_DLC2	57..120	CDD:188991
		SAM	61..120	CDD:197735
		RhoGAP_DLC1	675..892	CDD:239840	60/233 (26%)
		START_STARD13-like	919..1122	CDD:176918	4/16 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810