DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment conu and cv-c

DIOPT Version :9

Sequence 1:	NP_001036454.1	Gene:	conu / 3355133	FlyBaseID:	FBgn0039994	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	NP_001097786.1	Gene:	cv-c / 41749	FlyBaseID:	FBgn0285955	Length:	2351	Species:	Drosophila melanogaster

Alignment Length:	458	Identity:	105/458 - (22%)
Similarity:	182/458 - (39%)	Gaps:	77/458 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 KSRPKRKPDIRDVFREFDEQGTVTRSRSATP---DSLDSLQIDEAWTNNSLPTFVNVYEKNTETA 162
            :|.|||.|             |..||...:|   .|....|:.|..:::|...:.:..|.:|...
  Fly  1648 RSSPKRTP-------------TTPRSMRTSPLHFFSSPMSQLKEGKSDDSSSYYSDSQESSTGGK 1699

  Fly   163 IQCVEQSNEIYLKQNLRRTPSAPPKSGTYADIFRGSQVRC----DIPLYSADG----VELLGYSR 219
            :...:.|.   .::.|:||       |...||...|...|    .:.:..|:.    |::...:|
  Fly  1700 LSLRKPSK---ARRFLQRT-------GKVDDIGAHSDSECHQGRKLLIKDANSNTTEVKVKKLTR 1754

  Fly   220 IGTIQFPRNRSVSDPFCSIGRSKESRSENDARSQKKKSSEVLSASENECGRLLPMPYNVLSFESI 284
            .|::...::....|.|    ||...||.:.:|.:.|...:...|:.|...:..|: ....||:..
  Fly  1755 GGSLNLGKDPKKRDGF----RSSSFRSRSTSRKEAKNDEDTAGATTNGGSKRQPV-VRWHSFQME 1814

  Fly   285 CRDSSSLDSC-----EVL--DTCDIPSTLFTDVVLISETDMKRLQTILWLELATI---FDRNKVS 339
            .|.:.....|     |.|  |...:|         .:.....:||.|..|.|.|:   .:|...|
  Fly  1815 ERPNMIFRKCFSKKIEPLQEDAGGMP---------FAAMSAGQLQIIRKLALVTLTGHMERYCPS 1870

  Fly   340 --------LDK-RKPFKRRRKEEGNLFGVSINALIRRDQQVTGTDSSLVPLFLEKLIGELLRRGS 395
                    |.| .|..|....::..:|||.:..:::|..|.       :||.:......|.....
  Fly  1871 HRSGWNWELPKFIKKIKMPDYKDKKVFGVPLLMILQRSGQT-------LPLAVRAAFRWLQLNAL 1928

  Fly   396 REEGLLRIGGHKQKTELLYNELESTFYQNPDNLDNLFRTATVHELSSLLKRWLRELPQPLLTNEL 460
            .:.|:.|..|.|.:...|..::|.|  .:.....::|.....::::.:||::.||||:.|||.::
  Fly  1929 DQVGIFRKSGGKSRIMKLREQIEVT--DSTAECMDVFDLQQAYDVADMLKQYFRELPESLLTTKM 1991

  Fly   461 IQLFYQC-HTLPSIDQMNALSILCHLLPPENRNTLRSLLSFFNIIINLKDINKMNVHNVATIMAP 524
            .:.|... ..||:..:::|:.....|||.|||..|..||.|..|:......|:|..:|:...:|.
  Fly  1992 SETFVAIFQHLPAEVRLDAVQCAVLLLPDENREILYVLLEFLTIVAANSQQNQMTSNNLGVCLAQ 2056

  Fly   525 SMF 527
            |:|
  Fly  2057 SIF 2059

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	46/173 (27%)
cv-c	NP_001097786.1	SAM_DLC1,2-like	1382..1441	CDD:188937
		RhoGAP_DLC1	1893..2116	CDD:239840	46/176 (26%)
		SRPBCC	2148..2343	CDD:301327
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2200
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810