Protein Alignment conu and arhgap12b

DIOPT Version :9

• Sequence 1: NP_001036454.1
• Gene: conu / 3355133
• FlyBaseID: FBgn0039994
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_021335715.1
• Gene: arhgap12b / 393848
• ZFINID: ZDB-GENE-040426-1727
• Length: 882
• Species: Danio rerio
• Alignment Length: 625
• Identity: 131/625 - (20%)
• Similarity: 231/625 - (36%)
• Gaps: 176/625 - (28%)

  Fly    16 SEFLNEYYLQSNSQSIEPEASYEDGEMEAEWLVSAGYPELTK-----------PFEQGLEVSKKD 69
            ||:.||.:::...:...|.....||. .:||       ||.|           |....||  :|.
Zfish   357 SEYTNEKWIKHVDEQGRPYYYSADGS-RSEW-------ELPKYNLSPPISGEAPKSHSLE--RKQ 411

  Fly    70 LEPILTTLSKPHAEAIVQLVRTLNKTVRVRTK--------------SRPKRKPDIRDVFREFDEQ 120
            .|||:.|..: |:..::.:  :..::|..:..              |.|..|..:.:|.:..:..
Zfish   412 QEPIVLTKWR-HSTYVLDI--SDKESVNAKPNSPESDSCPSSPKHPSTPSEKCGVLNVTKITEHG 473

  Fly   121 GTVTRSRSATPDSLDSLQI--------DEAWT---NNSLPTFVNVYEKNTETAIQCVEQSNEIYL 174
            ..|.::.::|...|....:        ..:|:   |.|.|..:                   :.|
Zfish   474 KKVRKNWASTWTVLQGSSLLFAKGQGSGTSWSYCHNGSFPELL-------------------LSL 519

  Fly   175 KQNLRRT-PSAPPKSGTY-----ADIFRGSQVRCDIPLYSADGVELLGYSRIGTIQFPRNRSVSD 233
            ..|.:|: ...|..|.|:     |..|.|:|.:   |.::.|       .|.|::::
Zfish   520 LSNWKRSIKPRPAVSYTHCRRARASSFGGNQSK---PEFTVD-------LRGGSVEW-------- 566

  Fly   234 PFCSIGRSKESRSENDARSQKKK-SSEVLSASE-----NECGRLLPMPYNVLSFES---ICRDSS 289
                  .|||..|:......|.: .:|:|..||     |:..|.|....|..::||   |..|..
Zfish   567 ------ASKEKSSKKHVIELKTRVGTELLIQSEIDSVINDWFRALSETINTHAWESDEAIEEDMP 625

  Fly   290 SLDSCEVLDTCDIPSTLFTDVVLISETDMKRLQTILWLELATIFDRNKVSLDK---RKPFKRRRK 351
            .....|..|....|.....:.| :..:.|:..:.          .:.:|.|.|   |:|..:..:
Zfish   626 ESPGSEKHDKEKDPRDSKKNRV-VKNSSMESSEQ----------KKTRVKLKKFLTRRPTLQAVR 679

  Fly   352 EEG----NLFGVSINALIRRDQQVTGTDSSLVPLFLEKLIGELLRRGSREEGLLRIGGHK---QK 409
            ::|    .:||.|:.||.:|:    ||.   ||.|::..|..:...|...:||.|:.|:.   ||
Zfish   680 DKGYIKDQVFGCSLTALCQRE----GTS---VPNFVKMCIEHVENTGLNVDGLYRVSGNLAVIQK 737

  Fly   410 TELLYNELESTFYQNPDNLDNLFRTATVHELSSLLKRWLRELPQPLLT----NELIQLF----YQ 466
            .....|..|..      |||: .:...:|..:..||...||||:||.|    |:.::..    |:
Zfish   738 LRFAVNHDEKV------NLDD-SKWEDIHVTTGALKMLFRELPEPLFTYASFNDFVEAIKNSDYK 795

  Fly   467 CHTLPSIDQMNALSILCHLLPPENRNTLRSLLSFFNIIINLKDINKMNVHNVATIMAPSMFPPRY 531
                   .::.::..|...||..|:.|::.|......:|:..::|:|...:||.:..|::..|..
Zfish   796 -------QRVQSIKDLIKQLPKPNQETMKVLFKHLKRVIDHGEVNRMTTQSVAIVFGPTLLRPEI 853

  Fly   532 ------IHPSDNNSIAEQVRMAAQCCRLTNILILRGEKLF 565
                  :|....|.|.|             :::|..|.:|
Zfish   854 ETGNMAVHMVYQNQIVE-------------LILLEYENIF 880

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	56/227 (25%)
arhgap12b	XP_021335715.1	SH3_ARHGAP12	17..76	CDD:213003
		SH3-WW_linker	73..267	CDD:318759
		WW	271..297	CDD:306827
		WW	364..389	CDD:306827	6/32 (19%)
		PH_ARHGAP9-like	459..611	CDD:270053	35/194 (18%)
		RhoGAP_ARHGAP27_15_12_9	689..875	CDD:239868	53/219 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910