DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment conu and LOC365791

DIOPT Version :9

Sequence 1:	NP_001036454.1	Gene:	conu / 3355133	FlyBaseID:	FBgn0039994	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	XP_038959586.1	Gene:	LOC365791 / 365791	RGDID:	1359174	Length:	847	Species:	Rattus norvegicus

Alignment Length:	561	Identity:	108/561 - (19%)
Similarity:	194/561 - (34%)	Gaps:	208/561 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   199 QVRCDIP---LYSADGVELLGYSR---IGTIQFPRNRSVSDPFCSIG------RSKE-------- 243
            :::|.||   |:..|.|||:..::   ..||.|         :.:.|      ||:|
  Rat    46 KIKCIIPLNYLWVVDDVELVRANQTCTCKTIFF---------YWATGNALATFRSEEQKVQWYTF 101

  Fly   244 -SRSENDARSQKKKS-------SEVLSASENEC-------------GRLLPM------------- 274
             :||.::|:...||:       .::.:...:.|             .:||||
  Rat   102 LTRSISEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHNIEDYQLWF 166

  Fly   275 ----------------PYNVLSFESICRDSSSLDSCEVLDTCDIPSTLFTDVVLISETDMKRL-- 321
                            ||::: ..::..:.|..:           |.:||...|:....|:..
  Rat   167 SPGHKEAPRALQGHEYPYDII-MNNVQNNLSKSN-----------SKIFTAFPLLPGLFMENQSW 219

  Fly   322 ----QTILWLELATIFDRNKVSLDKRKPFKRRRK-----------------------EEGNLFGV 359
                |.||       ..|:.....::...|||||                       :.|.|||.
  Rat   220 DTGGQFIL-------KPRDSAGSQQQDAKKRRRKSCMTSCFHGGCVPHHDQECIRDDKRGKLFGQ 277

  Fly   360 SINALIRRDQQVTGTDSSLVPLFLEKLIGELLRRGSREEGLLRI--GGHKQKT--ELLYNELEST 420
            .::::.:        |..|..:.|: ::..:..:|...:.:..|  .|...||  |.|.|.....
  Rat   278 DLSSICQ--------DGKLPTIILD-MLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVD 333

  Fly   421 FYQNPDNLDNLFRTATVHELSSLLKRWLRELPQPLLTNELIQLFYQCHTLP----SIDQMNALSI 481
            .||.|           ||.::.:||.:|:.:...|||:   :|:.|...:|    ..:::.|:..
  Rat   334 IYQQP-----------VHVVAWILKEFLQSIKGSLLTS---KLYDQWLIVPEKVNDKEKLAAVKS 384

  Fly   482 LCHLLPPENRNTLRSLLSFFNIIINLKDINKMNVHNVATIMAPS-MFPPRYIHPSDNNSIAEQVR 545
            |...||..|.:.||.|....:.|.....:|.|:...::...||. ::.|.|.:....|.||:::.
  Rat   385 LLEKLPKPNADLLRQLFRILHQIKTNSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKIS 449

  Fly   546 MAAQCCRLTNILILRGE---------KLFQVP-------------NNLIVESQKTMMGKKGWHRH 588
            :..  ..:.|...|.||         .|:..|             |.::.|::..:....|
  Rat   450 LVT--FMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPG---- 508

  Fly   589 RNSNEITAKP-------SGKASNV----------GVGHDST 612
                |.|..|       ||.|:::          |.|::||
  Rat   509 ----ERTCTPDFDELPRSGAAASIPYEGILASEKGEGNEST 545

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	54/250 (22%)
LOC365791	XP_038959586.1	PH-like	6..102	CDD:418428	15/64 (23%)
		Ubiquitin_like_fold	115..230	CDD:421700	17/133 (13%)
		RhoGAP_ARHGAP20	274..466	CDD:239867	50/216 (23%)
		RhoGAP_ARHGAP20	562..766	CDD:239867
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910