Protein Alignment conu and Arhgap21

DIOPT Version :9

• Sequence 1: NP_001036454.1
• Gene: conu / 3355133
• FlyBaseID: FBgn0039994
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001178622.1
• Gene: Arhgap21 / 307178
• RGDID: 1311028
• Length: 1952
• Species: Rattus norvegicus
• Alignment Length: 655
• Identity: 136/655 - (20%)
• Similarity: 247/655 - (37%)
• Gaps: 159/655 - (24%)

  Fly    24 LQSNSQSIEPEASYEDGEMEAEWLVSAGYPELTKPFEQGLEVSKKDLEPILTTLSKPHAEAIVQL 88
            |..:.:|:.|.:.  ||:..::       .|.:|.:::||:..::|.:     ||..|..::
  Rat   859 LSHDQESVGPPSL--DGQHTSK-------TERSKSYDEGLDDYREDAK-----LSFKHVSSL--- 906

  Fly    89 VRTLNKTVRVRTKSRP-----KRKPDIRDVFREFDEQGTVTRSRSATPDSLDSLQIDEAWTNNSL 148
                 |.:::....:.     .||....:||.:..::|.: :.|....|....:       ..|:
  Rat   907 -----KGIKIADSQKSSEDSGSRKDSSSEVFSDAAKEGWL-QFRPLVTDKGKRV-------GGSI 958

  Fly   149 PTFVNVYEKNTETAIQCVEQSNEIYLKQNLRR--TPSAPPK---------SGTYAD-----IFRG 197
            ..:..:|         .|.:.:.:||.::.|.  |||...:         ..:|::     :||.
  Rat   959 RPWKQMY---------VVLRGHSLYLYKDRREQTTPSEEEQPISVNACLIDISYSETKRRNVFRL 1014

  Fly   198 SQVRCDIPLYSADGVELLGYSRIGTIQFPRNRSVSDPFCSIGRSKESRSENDARSQK-KKSSEVL 261
            :...|:....:.|..::|.:  |.|||...|.:..|         ...:..|..|:: |:.:.:|
  Rat  1015 TTSDCECLFQAEDRDDMLAW--IKTIQESSNLNEED---------TGVTNRDLISRRIKEYNSLL 1068

  Fly   262 SASENECGRLLPMPYNVLSFESICRDSSSLDSCEVLDTCDIPSTLF-------TDVVLISETDM- 318
            |.:|    :|...|...||...           .:|.....|.|..       ::..|:|:.|.
  Rat  1069 SKTE----QLPKTPRQSLSIRQ-----------TLLGAKSEPKTQSPHSPKEESERKLLSKDDTS 1118

  Fly   319 --KRLQTILWLELATIFDRNKVSLDKRKPFKRRRKEEGNLFGVSINALIRRDQQVTGTDSSLVPL 381
              |...|  |        |..:....||.|:::....|. |||      |.|.......:..:||
  Rat  1119 PPKDKGT--W--------RRGIPSIVRKTFEKKPAATGT-FGV------RLDDCPPAHTNRYIPL 1166

  Fly   382 FLE---KLIGELLRRGSREEGLLRIGGHKQKTELLYNELESTFYQNPDNLDNLFRTATVHELSSL 443
            .::   ||:.|   ||....|:.|:.|:......:..||.... .:.|..|:.:|...|  :|||
  Rat  1167 IVDICCKLVEE---RGLEYTGIYRVPGNNAAISSMQEELNKGM-ADIDIQDDKWRDLNV--ISSL 1225

  Fly   444 LKRWLRELPQPLLTNELIQLFYQCHTLPS-IDQMNALSILCHLLPPENRNTLRSLLSFFNIIINL 507
            ||.:.|:||:||.||:....|.:.:.... :|::..|..|.|.||..:..||:.|.:....:...
  Rat  1226 LKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLRTLKRLIHDLPEHHFETLKFLSAHLKTVAEN 1290

  Fly   508 KDINKMNVHNVATIMAPSMFPPRYIHPSDNNSIAEQVRMAAQCCRLTNILILRGEKLF------- 565
            .:.|||...|:|.:..|::     :..|::|.......|..| .::...||...:..|
  Rat  1291 SEKNKMEPRNLAIVFGPTL-----VRTSEDNMTHMVTHMPDQ-YKIVETLIQHHDWFFTEEGAEE 1349

  Fly   566 --------------QVPNNLIVESQKTMMGKKGWHRHRNSNEITAKPSGKASNVGVGHDSTVINK 616
                          .|||   ::...|.:|:.|......|:..|:..:....:.|.|.|     :
  Rat  1350 PLTAVQEENTVDSQPVPN---IDHLLTNIGRTGVLPGDVSDSATSDSTKSKGSWGSGKD-----Q 1406

  Fly   617 YSTNL 621
            ||..|
  Rat  1407 YSREL 1411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	59/244 (24%)
Arhgap21	NP_001178622.1	PDZ_signaling	52..159	CDD:238492
		PH_ARHGAP21-like	936..1045	CDD:269955	23/127 (18%)
		PH	937..1042	CDD:278594	22/123 (18%)
		RhoGAP_ARHGAP21	1147..1342	CDD:239860	55/213 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910