DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment conu and Arhgap22

DIOPT Version :9

Sequence 1:	NP_001036454.1	Gene:	conu / 3355133	FlyBaseID:	FBgn0039994	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	XP_038950392.1	Gene:	Arhgap22 / 306279	RGDID:	1307237	Length:	722	Species:	Rattus norvegicus

Alignment Length:	262	Identity:	72/262 - (27%)
Similarity:	121/262 - (46%)	Gaps:	35/262 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   356 LFGVSINALIRRDQQVTGTDSSLVPLFLEKLIGELLRRGSREEGLLRIGGHKQKTELLYNELEST 420
            :||..:...:..:::.   ...|.||.:|:.:..:..||..||||.|:.|...    |..:|:.:
  Rat   174 IFGQRLEDTVHHERKF---GPRLAPLLVEQCVDFIRERGLSEEGLFRMPGQAN----LVRDLQDS 231

  Fly   421 F--YQNPDNLDNLFRTAT-VHELSSLLKRWLRELPQPLLTNELIQLFYQCHTLPSIDQMNA---L 479
            |  .:.|     ||.:.| ||.::||||.:|||||:|::.....:.|..|..|.:.|:...   |
  Rat   232 FDCGEKP-----LFDSTTDVHTVASLLKLYLRELPEPVIPFARYEDFLSCAQLLTKDEGEGTVEL 291

  Fly   480 SILCHLLPPENRNTLRSLLSFFNIIINLKDINKMNVHNVATIMAPSMFPPRYIHP---SDNNSIA 541
            :.....||..|.|.||.:..|.:.:....|:|||:|.|:||:..|::..|:...|   .:..|:.
  Rat   292 AKQVSNLPQANYNLLRYICRFLDEVQAHSDVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLV 356

  Fly   542 EQVRMAAQCCRLTNILILRGEKLFQVPNNLIVESQK-TMMGKKGWHRHRNSNEITAKPSGKASNV 605
            :         .|..:||.:..:||..|:.....|.: |:.|...|    .|.|:|....|:..:.
  Rat   357 Q---------HLMTVLIRKHGQLFATPSFEEPASPRGTVQGTVEW----GSEEVTRDHQGEPGSS 408

  Fly   606 GV 607
            |:
  Rat   409 GL 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	63/228 (28%)
Arhgap22	XP_038950392.1	PH-like	42..157	CDD:418428
		RhoGAP_ARHGAP22_24_25	173..371	CDD:239855	60/217 (28%)
		SMC_prok_B	<614..>704	CDD:274008
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910