Protein Alignment conu and Arhgap28

DIOPT Version :9

• Sequence 1: NP_001036454.1
• Gene: conu / 3355133
• FlyBaseID: FBgn0039994
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001178744.1
• Gene: Arhgap28 / 301709
• RGDID: 1559882
• Length: 726
• Species: Rattus norvegicus
• Alignment Length: 624
• Identity: 162/624 - (25%)
• Similarity: 270/624 - (43%)
• Gaps: 115/624 - (18%)

  Fly     1 MNSNTDLH-----HSDDQ---DFSEFLNEYYLQSNS---------QSIEPEASYE-----DGEME 43
            |.||..||     .|:.|   |.|..:.|::.:.:|         :...|.|..|     :||:|
  Rat    51 MLSNESLHPPTFSRSNSQASVDSSTSVEEFWKEISSIKESSIGGQEEQSPTAPTEVKPVDEGELE 115

  Fly    44 AEWLVSAGYPELTKPFEQGLEVSKKDLEPILTTLSKPHAEAIVQLVRTLNKTVRVRTKSRPKRKP 108
            ||||...|...|....|:      :|.:.:|:||::..|.|:.:...|..:|:|.:.|...:
  Rat   116 AEWLQDVGLSTLISGDEE------EDGKALLSTLTRTQAAAVKKRYNTYTQTLRKKNKQAIR--- 171

  Fly   109 DIRDVFREFDEQGTVTRSRSATPDSLD-SLQIDEAWTNNSLPTFVNVYEKNTETA-IQCVEQSNE 171
            |:||||      |.   |.|...||.: :.|:|.......||..........:.| :.....||
  Rat   172 DVRDVF------GV---SESPPSDSCEHATQLDSTKEEKDLPGVTKTSRPLPDDASLNSTTLSN- 226

  Fly   172 IYLKQNLRRTPSAPPKSGTYADIFRGS----QVRCDIPLY---SADGVELLGYSRIGTIQFPRNR 229
                       .|..:.|.:..:..||    :...|||::   |||..:        ::|    |
  Rat   227 -----------GAQDEEGGFVALQSGSVSILEAIPDIPVHTNGSADTEQ--------SVQ----R 268

  Fly   230 SVSDPFCSIGRSKESRSENDARSQKKKSSEVLSASENECGRLLPMPYNVLSFESICRDSSSLDSC 294
            .:||   .....|....|.:..|.:...|||::.:.:.         |......|.::.
  Rat   269 GLSD---DDYLEKNIPPEAEELSFEVSYSEVVTETPDR---------NKWKKSDIKKED------ 315

  Fly   295 EVLDTCDIPSTLF--TDVVLISETDMKRLQTILWLELATIFDRNKVSLDKRKPFKRRRKEEGNLF 357
            .||....:..|.|  |:...:|..|||:::.:..:||...||..::.| ||...:|.|..:..:|
  Rat   316 YVLPKFIVQKTRFGLTETGDLSAEDMKKIRHLSLIELTAFFDAFRIQL-KRNKTERVRGRDNGIF 379

  Fly   358 GVSINALIRRDQQVTGTDSSL-VPLFLEKLIGELLRRGSREEGLLRIGGHKQKTELLYNELESTF 421
            ||.:..|:..|::   .|.:: |||.|:|...::...|...||:.|:.|...|.:....||::.|
  Rat   380 GVPLTVLLDNDRK---KDPAVKVPLVLQKFFQKVEESGLESEGIFRLSGCTAKVKQYREELDARF 441

  Fly   422 YQNPDNLDNLFRTATVH-ELSSLLKRWLRELPQPLLTNELIQLFYQ-CHTLPSID-QMNALSILC 483
                 |.|........| |.:.:||.:.||||..|...|.|..|.. ....|.|. |..||.::.
  Rat   442 -----NTDKFKWDKMCHREAAVMLKAFFRELPTSLFPIEYIPAFISLMERGPDIKVQFQALHLMV 501

  Fly   484 HLLPPENRNTLRSLLSFFNIIINLKDINKMNVHNVATIMAPSMFPPRYIHPSDNNSIAEQVRMAA 548
            ..||..||:|.::|::|||.:|..:..|:|::.|::|:|||::|..|..|     |..|::.:|.
  Rat   502 MALPDANRDTAQALMTFFNKVIANESKNRMSLWNISTVMAPNLFFSRSKH-----SDCEELLVAN 561

  Fly   549 QCCRLTNILILRGEKLFQVPNNLIVE----SQKTMMGKK 583
            ....:..:::...:.|::||:.||.:    ::.||:.||
  Rat   562 TAAHIIRLMLTYQKILWKVPSFLITQVRRMNEATMLLKK 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	67/227 (30%)
Arhgap28	NP_001178744.1	RhoGAP_ARHGAP18	378..589	CDD:239856	67/223 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342452
Domainoid	1	1.000	109	1.000	Domainoid score	I6215
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	186	1.000	Inparanoid score	I3829
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D309300at33208
OrthoFinder	1	1.000	-	-		FOG0002326
OrthoInspector	1	1.000	-	-		otm46373
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR14963
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	10.000