DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment conu and Arhgap31

DIOPT Version :9

Sequence 1:	NP_001036454.1	Gene:	conu / 3355133	FlyBaseID:	FBgn0039994	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	NP_001099349.1	Gene:	Arhgap31 / 288093	RGDID:	1306093	Length:	1428	Species:	Rattus norvegicus

Alignment Length:	243	Identity:	60/243 - (24%)
Similarity:	105/243 - (43%)	Gaps:	17/243 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   342 KRKPFKRRRKEEG--NLFGVSINALIRRDQQVTGTDSSLVPLFLEKLIGELLRRGSREEGLLRIG 404
            |.|..|::.|.:|  :.||..:...:    :.:|.|   ||..| |...|.:......:|:.|:.
  Rat     2 KNKGAKQKLKRKGAASAFGCDLTEYL----ESSGQD---VPYVL-KSCAEFIETHGIVDGIYRLS 58

  Fly   405 GHKQKTELLYNELESTFYQNPDNLDNLFRTATVHELSSLLKRWLRELPQPLLTNELIQLFYQCHT 469
            |.....:.|..|..|.  |.||....:: ...:|.:.||.|.:.||||.||||.||.:.|.:..:
  Rat    59 GVTSNIQRLRQEFGSD--QCPDLTREVY-LQDIHCVGSLCKLYFRELPNPLLTYELYEKFTEAVS 120

  Fly   470 -LPSIDQMNALSILCHLLPPENRNTLRSLLSFFNIIINLKDINKMNVHNVATIMAPSMFPPRYIH 533
             .|...|:..:..:...|||.:..||..|:.....|.:......|:..|:|.:.||::...:.|.
  Rat   121 HCPEEGQLARIQNVIQELPPPHYRTLEYLIRHLAHIASFSSKTNMHARNLALVWAPNLLRSKKIE 185

  Fly   534 PSDNNSIAEQVRMAAQCCRLTNILILRGEKLFQ--VPNNLIVESQKTM 579
            .:..|..|..:.:..|.. :...::...:::|.  .|..|..:..:|:
  Rat   186 ATICNGDAAFLAVRVQQV-VIEFILNHADQIFNGGAPGALQQDESRTI 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	54/222 (24%)
Arhgap31	NP_001099349.1	RhoGAP_CdGAP	17..211	CDD:239849	51/205 (25%)
Arhgap31	NP_001099349.1	DUF966	<1189..>1306	CDD:283735
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910