Protein Alignment conu and Arhgap28

DIOPT Version :9

• Sequence 1: NP_001036454.1
• Gene: conu / 3355133
• FlyBaseID: FBgn0039994
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_036016523.1
• Gene: Arhgap28 / 268970
• MGIID: 2147003
• Length: 756
• Species: Mus musculus
• Alignment Length: 624
• Identity: 161/624 - (25%)
• Similarity: 259/624 - (41%)
• Gaps: 142/624 - (22%)

  Fly     1 MNSNTDLH-----HSDDQ-------DFSEFLNEYYLQS-------NSQSIEPEAS--------YE 38
            |.||..||     .|:.|       ...|||.|  ::|       .||...|.|:        .:
Mouse   108 MLSNESLHPPSFSRSNSQASVDSSASMEEFLRE--IESIKESSVGASQEQPPTAAAAAAEVKPVD 170

  Fly    39 DGEMEAEWLVSAGYPELTKPFEQGLEVSKKDLEPILTTLSKPHAEAIVQLVRTLNKTVRVRTKSR 103
            :||:|||||...|...|....|:      :|.:.:|:||::..|.|:.:...|..:|:|.:.| :
Mouse   171 EGELEAEWLQDVGLSTLISGNEE------EDGKALLSTLTRTQAAAVKKRYNTYTQTLRKKNK-Q 228

  Fly   104 PKRKPDIRDVFREFDEQGTVTRSRSATPDSLD-SLQIDEAWTNNSLPTFVNVYEKNTETAIQCVE 167
            |.|  |:||:|      |.   |.|...||.: :.|:|.......||...     .|...:..:|
Mouse   229 PVR--DVRDIF------GV---SESPPSDSCEHATQLDGTKEEKDLPGVT-----KTSRPLSILE 277

  Fly   168 QSNEIYLKQNLRRTPSAPPKSGTYADIFRGSQVRCDIPLYSADGVEL---LGYSRIGTIQFPRNR 229
            ...:|.:..|.........:|....|.:.|..|       .|:..||   :.||.:.|....||:
Mouse   278 AIPDIAVHTNGSADAEQSVQSTLSDDDYHGKNV-------PAEAEELSFEVSYSEMVTEMPDRNK 335

  Fly   230 SVSDPFCSIGRSKESRSENDARSQKKKSSEVLSASENECGRLLPMPYNVLSFESICRDSSSLDSC 294
            .                   .:|..||...||:       :.:
Mouse   336 W-------------------KKSDIKKEDYVLT-------KFI---------------------- 352

  Fly   295 EVLDTCDIPSTLF--TDVVLISETDMKRLQTILWLELATIFDRNKVSLDKRKPFKRRRKEEGNLF 357
                   |..|.|  |:...:|..|||:::.:..:||...||...:.| ||...:|.|..:..:|
Mouse   353 -------IQKTRFGLTETGDLSVEDMKKIRHLSLIELTAFFDAFGIQL-KRNKTERVRGRDNGIF 409

  Fly   358 GVSINALIRRDQQVTGTDSSL-VPLFLEKLIGELLRRGSREEGLLRIGGHKQKTELLYNELESTF 421
            ||.:..|:..|::   .|.:: |||.|:|...::...|...||:.|:.|...|.:....||::.|
Mouse   410 GVPLTVLLDNDRK---KDPAVKVPLVLQKFFQKVEESGLESEGIFRLSGCTAKVKQYREELDARF 471

  Fly   422 YQNPDNLDNLFRTATVH-ELSSLLKRWLRELPQPLLTNELIQLFYQ-CHTLPSID-QMNALSILC 483
                 |.|........| |.:.:||.:.||||..|...|.|..|.. ....|.|. |..||.::.
Mouse   472 -----NADKFKWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPDIKVQFQALHLMV 531

  Fly   484 HLLPPENRNTLRSLLSFFNIIINLKDINKMNVHNVATIMAPSMFPPRYIHPSDNNSIAEQVRMAA 548
            ..||..||:|.::|::|||.:|..:..|:||:.|::|:|||::|..|..|     |..|::.:|.
Mouse   532 MALPDANRDTAQALMAFFNKVIANESKNRMNLWNISTVMAPNLFFSRSKH-----SDCEELLLAN 591

  Fly   549 QCCRLTNILILRGEKLFQVPNNLIVE----SQKTMMGKK 583
            ....:..:::...:.|::||:.||.:    ::.||:.||
Mouse   592 TATHIIRLMLKYQKILWKVPSFLITQVRRMNEATMLLKK 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	68/227 (30%)
Arhgap28	XP_036016523.1	RhoGAP_ARHGAP18	408..619	CDD:239856	68/223 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838663
Domainoid	1	1.000	110	1.000	Domainoid score	I6305
eggNOG	1	0.900	-	-		E1_KOG2200
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	187	1.000	Inparanoid score	I3900
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D309300at33208
OrthoFinder	1	1.000	-	-		FOG0002326
OrthoInspector	1	1.000	-	-		otm44275
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR14963
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.860