DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment conu and Arhgap24

DIOPT Version :9

Sequence 1:NP_001036454.1 Gene:conu / 3355133 FlyBaseID:FBgn0039994 Length:629 Species:Drosophila melanogaster
Sequence 2:XP_036020963.1 Gene:Arhgap24 / 231532 MGIID:1922647 Length:804 Species:Mus musculus


Alignment Length:457 Identity:102/457 - (22%)
Similarity:173/457 - (37%) Gaps:145/457 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   220 IGTIQFPRNRSVSDPFCSIGRSKESRSENDAR--------SQKKKSSEVLSASENECGRLLPMPY 276
            :|||....|:.:..| |:        .||..:        :|.::|:.|      |...|.|:|.
Mouse    58 LGTIFLHGNKVIEHP-CN--------EENPGKFLFEVVPGAQSEESAIV------ELVVLKPLPI 107

  Fly   277 NVLSFESICRDSSSLDSCEVLDTCDIPSTLFTDVVLI---------------------------- 313
                  |...|:.:.....:...|    .|:|.|.|:                            
Mouse   108 ------SGATDNGAAWQRSIQTFC----FLWTSVSLLADQNSELQGPGGERDRMTANHESYLLMA 162

  Fly   314 -SETDM----KRLQTILWLELATIFDRNKVSLDKRKPFKRRRKEEGNLFGVSINALIRRDQQVTG 373
             ::.||    |.::.::|                 .||      .|.:||..:...:|.:::.  
Mouse   163 STQNDMEDWVKSIRRVIW-----------------GPF------GGGIFGQKLEDTVRYEKRY-- 202

  Fly   374 TDSSLVPLFLEKLIGELLRRGSREEGLLRIGGHKQKTELLYNELESTF--YQNP---DNLDNLFR 433
             .:.|.|:.:|:.:..:.:||.:||||.|:.|...    |..||:..|  .:.|   .|.|    
Mouse   203 -GNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQAN----LVKELQDAFDCGEKPSFDSNTD---- 258

  Fly   434 TATVHELSSLLKRWLRELPQPLLTNELIQLFYQCHTLPSIDQ---MNALSILCHLLPPENRNTLR 495
               ||.::||||.:|||||:|::.....:.|..|.||.|.::   :..|......||..|.|.|:
Mouse   259 ---VHTVASLLKLYLRELPEPVVPYAKYEDFLSCATLLSKEEEAGVKELMKQVKSLPVVNYNLLK 320

  Fly   496 SLLSFFNIIINLKDINKMNVHNVATIMAPSMFPPRYIHPSDNNSIAEQVRMAAQCCRLTNILILR 560
            .:..|.:.:.:...:|||:..|:||:..|::..|:.   .|..:|.|...:..|   |.:::|.:
Mouse   321 YICRFLDEVQSYSGVNKMSAQNLATVFGPNILRPKV---EDPLTIMEGTVVVQQ---LMSVMISK 379

  Fly   561 GEKLFQVPNNLIVESQKTMMGKKGWHRHRNSNEITAKP-SGKASNVGVGHDSTVI----NKYSTN 620
            .::||.                       ...|..:|| .|..||...||....:    ||.:.|
Mouse   380 HDRLFP-----------------------KDTEPQSKPQDGPNSNNNDGHKKATMGQLQNKENNN 421

  Fly   621 LK 622
            .|
Mouse   422 TK 423

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
conuNP_001036454.1 RhoGAP_ARHGAP18 356..576 CDD:239856 61/227 (27%)
Arhgap24XP_036020963.1 PH-like 20..186 CDD:418428 28/175 (16%)
RhoGAP_ARHGAP22_24_25 186..384 CDD:239855 59/217 (27%)
Smc <705..>791 CDD:224117
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

Return to query results.
Submit another query.