Protein Alignment conu and ARHGAP27

DIOPT Version :9

• Sequence 1: NP_001036454.1
• Gene: conu / 3355133
• FlyBaseID: FBgn0039994
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_011522770.1
• Gene: ARHGAP27 / 201176
• HGNCID: 31813
• Length: 922
• Species: Homo sapiens
• Alignment Length: 525
• Identity: 118/525 - (22%)
• Similarity: 200/525 - (38%)
• Gaps: 120/525 - (22%)

  Fly    36 SYEDGEMEAEWLVSAGYPELTKPFEQGLEVSKKDLEPILTTLSKPHAEAIVQLVRTLNKTVRVRT 100
            |.:||:..|:    |..||...|.|.....|.:::.|                     .|..|||
Human   455 SSQDGDTPAQ----ASPPEEKVPAELDEVGSWEEVSP---------------------ATAAVRT 494

  Fly   101 KSRPKRKPDIRDVFREFDEQGTVTRSRSATPDS-LDSLQIDEAWTNNSLPTFVNVYEKNTETAI- 163
            |:              .|:.|.:.|:::|.... |.......:||  .|...|..:.|:::|:.
Human   495 KT--------------LDKAGVLHRTKTADKGKRLRKKHWSASWT--VLEGGVLTFFKDSKTSAA 543

  Fly   164 ----QCVEQSNEIYLKQNLRRTPSAPPKSGTYADIFRGSQVRCDIPLYSADGVELLGYSRIGTIQ 224
                |..:.|...|..:....|.|..||.        .|..:..:.|.|.||.|.|.......|.
Human   544 GGLRQPSKFSTPEYTVELRGATLSWAPKD--------KSSRKNVLELRSRDGSEYLIQHDSEAII 600

  Fly   225 FPRNRSVSDPFCSIGRSKESRSEN--------DARSQKKKSSEV-------LSASENECGRLLPM 274
            ...:::::.....:| |.:.|..|        .|...:.:.||.       |...|:|..|
Human   601 STWHKAIAQGIQELG-SMQLREVNVLRLTGGGPAAGSRPRLSEAMGIQSAELPPEESESSR---- 660

  Fly   275 PYNVLSFESICRDSSSLDSCEVLDTCDIPSTLFTDVVLIS-ETDMKRLQTILWLELATIFDRNKV 338
                :.|.|    |..|.|.:..:....|:.....:..:. |:|:.::             |:|:
Human   661 ----VDFGS----SERLGSWQEKEEDARPNAAAPALGPVGLESDLSKV-------------RHKL 704

  Fly   339 -SLDKRKPFKRRRKEEG----NLFGVSINALIRRDQQVTGTDSSLVPLFLEKLIGELLRRGSREE 398
             ...:|:|..:..:|:|    .:||.::.||..|::       |.||.|:::.|..:..||...:
Human   705 RKFLQRRPTLQSLREKGYIKDQVFGCALAALCERER-------SRVPRFVQQCIRAVEARGLDID 762

  Fly   399 GLLRIGGHKQKTELLYNELESTFYQNPDNLD-NLFRTATVHELSSLLKRWLRELPQPLLTNELIQ 462
            ||.||.|:....:.|..:::     :.:.|| :..|...||.::..||.:.||||:||......:
Human   763 GLYRISGNLATIQKLRYKVD-----HDERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFR 822

  Fly   463 LFYQCHTLPSIDQ---MNALSILCHLLPPENRNTLRSLLSFFNIIINLKDINKMNVHNVATIMAP 524
            .|.....|.  ||   ...:..|...||..|.:|||.|......:|...:.|:|:|.:||.:..|
Human   823 QFIAAIKLQ--DQARRSRCVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGP 885

  Fly   525 SMFPP 529
            ::..|
Human   886 TLLRP 890

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	51/178 (29%)
ARHGAP27	XP_011522770.1	SH3_ARHGAP27	10..66	CDD:213002
		WW	247..278	CDD:278809
		WW	417..443	CDD:197736
		PH_ARHGAP9-like	499..613	CDD:270053	25/123 (20%)
		PH	499..611	CDD:278594	25/121 (21%)
		RhoGAP_ARHGAP27_15_12_9	728..914	CDD:239868	51/177 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910