DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment conu and rrc-1

DIOPT Version :9

Sequence 1:	NP_001036454.1	Gene:	conu / 3355133	FlyBaseID:	FBgn0039994	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	NP_001024683.1	Gene:	rrc-1 / 181195	WormBaseID:	WBGene00009800	Length:	759	Species:	Caenorhabditis elegans

Alignment Length:	318	Identity:	78/318 - (24%)
Similarity:	130/318 - (40%)	Gaps:	72/318 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   309 DVVLISE--TDMKRLQTILWLELATI-------------------FDRNKVSL--DKRKP----- 345
            |:|.|:|  |.....|| .|....||                   |.|:.|.|  |||.|
Worm   189 DIVSITEMSTASPSEQT-FWKAKLTISNQKIVDPQNARLGFEIGYFPRDCVMLIDDKRLPNPLNN 252

  Fly   346 ----------------FKRRRKEEGNLFGVSINALIRRDQQVTGTDSSLVPLFLEKLIGELLRRG 394
                            |:.||:|.  :||:.:..|..|    ||   ..||:.:||....:..:|
Worm   253 EQKASTRNARRYMTTMFRNRRREP--IFGLELTDLYMR----TG---KKVPVIVEKCCASIEDQG 308

  Fly   395 SREEGLLRIGGHKQKTELLYNELESTFYQNPDNLDNLFRTATVHELSSLLKRWLRELPQPLLTNE 459
            . ..|:.|..|.:...:.|..:.:|.  ..||..:  |....::.:|||||::.|:||.||.|.:
Worm   309 I-VTGIYRQCGIQSNIQRLRAKFDSG--AEPDLHE--FGQRDIYSVSSLLKQYFRQLPNPLFTYQ 368

  Fly   460 ----LIQLFYQCHTLPSIDQMNALSILCHLLPPENRNTLRSLLSFFNIIINLKDINKMNVHNVAT 520
                ||:.|.:..:|.  :::.:|......:|..:..|.:.|:.....:...|.:..|...|:|.
Worm   369 AYPKLIEAFEKEDSLS--EKVESLRFSLETMPEAHYRTAKFLMEHLTRLCKSKSLTDMTSKNLAI 431

  Fly   521 IMAPSMF-PPRYIHPSDNNSIAEQVRMAAQCCRLTNILILRGEKLFQVPNNLIVESQK 577
            :.:|::| ||..::.:|.:.::......|.|    :..|...|.||  .|::..|..|
Worm   432 VWSPNLFRPPPTLNGADTHLLSGLNVHTAIC----DFFIENSESLF--VNDIDEEQSK 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	55/224 (25%)
rrc-1	NP_001024683.1	PX_domain	41..146	CDD:295365
		SH3	168..238	CDD:302595	12/49 (24%)
		RhoGAP	276..466	CDD:295372	49/209 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910