DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment conu and chin-1

DIOPT Version :9

Sequence 1:	NP_001036454.1	Gene:	conu / 3355133	FlyBaseID:	FBgn0039994	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	NP_497323.3	Gene:	chin-1 / 175268	WormBaseID:	WBGene00015267	Length:	421	Species:	Caenorhabditis elegans

Alignment Length:	177	Identity:	49/177 - (27%)
Similarity:	80/177 - (45%)	Gaps:	19/177 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   356 LFGVSINALIRRDQQVTGTD-SSLVPLFLEKLIGELLRRGSREEGLLRIGGHKQKTELLYNELES 419
            :|||.|..|.    ...|.| ..:|||    .|||:..||...||:.|:.|.....|.|..:.:|
Worm   231 MFGVDITTLC----MAHGADLPPIVPL----CIGEVESRGLDVEGIYRVSGSYDHMEKLKQQFDS 287

  Fly   420 TFYQNPDNLDNLFRTATVHELSSLLKRWLRELPQPLLT----NELIQLFYQCHTLPSIDQMNALS 480
            ..|.      :|.....:|.:..|||.:.|.|||.|:.    .:|:..:.:.:...:.::...:.
Worm   288 NQYV------DLATVCDIHTVCGLLKLYFRLLPQQLIPFSVHKQLLVAYQETNQRSTHERERQIR 346

  Fly   481 ILCHLLPPENRNTLRSLLSFFNIIINLKDINKMNVHNVATIMAPSMF 527
            .:...|...|..||.::|:....:.:....|||.|.|:|||.:|::|
Worm   347 KVMMELSDANIITLGAVLAHLKKVADHSAKNKMTVENLATIFSPTLF 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	49/177 (28%)
chin-1	NP_497323.3	SH2_a2chimerin_b2chimerin	43..130	CDD:198215
		C1_1	172..224	CDD:278556
		RhoGAP	248..413	CDD:238090	42/156 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910