Protein Alignment conu and hum-7

DIOPT Version :9

• Sequence 1: NP_001036454.1
• Gene: conu / 3355133
• FlyBaseID: FBgn0039994
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001248880.1
• Gene: hum-7 / 171650
• WormBaseID: WBGene00002040
• Length: 1880
• Species: Caenorhabditis elegans
• Alignment Length: 569
• Identity: 121/569 - (21%)
• Similarity: 210/569 - (36%)
• Gaps: 135/569 - (23%)

  Fly    93 NKTVRVRTKSR---PKRKPDI-----RDVFREFDEQGTVTRSRSATPDSLDSLQIDEAWTNNSLP 149
            |.|..||:.:|   |||..|:     |.........||.:.:::       ..|||..
 Worm  1285 NPTSPVRSPTRLHSPKRPWDLMPHKQRQSSSPIPSTGTFSLTKT-------KQQIDPG------- 1335

  Fly   150 TFVNVYEKNTETAIQCVEQSNEIYLKQNLRRTPSAPPKSGTYAD-IFRGSQVRCDIPLYSADGVE 213
               |:..::|:...|.     .|::....|....:..|..|..| :|:.|        ..|..:|
 Worm  1336 ---NMLVESTDDLRQF-----SIFIFNKTRHLNESNAKRDTVVDAVFKKS--------LRAFHME 1384

  Fly   214 LLGYSRI---------------------------GTIQFPRNRSVS------DPFCSIGRSKESR 245
            ||||..:                           .::.||....|:      :.:..:...|:..
 Worm  1385 LLGYEAVLSVEQSVLKYRDVITMFEGLLTKVCLEESVSFPTTLGVNAFRGFLNEYVHVQSKKKRG 1449

  Fly   246 SENDARSQKKKSSEVLS--ASENECGRLLPMPYNVLSFESICRDSSSLDSCEVLDTCDIPSTLFT 308
            .|..:..:|.....|.|  |:.:...|......:|.::..:|  :..:...|.|.||
 Worm  1450 KEKSSMIKKVGKKRVKSDVAAVHAGHRFRAEAVHVPTYCEVC--NQLIWHHEKLYTC-------- 1504

  Fly   309 DVVLISETDMKRLQTILWLELATIFDRNKVSLDKRKPFKRRRK------EEGNLFGVSINALIRR 367
              |....:..|:.|.             ||:    .|.:...|      ..|..||.|:.:::
 Worm  1505 --VACRISCHKKCQP-------------KVT----HPCQMTGKAIDPKTNGGRFFGASLVSIV-- 1548

  Fly   368 DQQVTGTDSSLVPLFLEKLIGELLRRGSREEGLLRIGGHKQKTELLYNELESTFYQNPDNLDNLF 432
                  .|...||..|::|...:..|....||:.|..|...:...:...:|||...:..||:::
 Worm  1549 ------DDDHTVPTLLDRLFFAIETRALFVEGVYRKSGSLPQVRSIRKVIESTADADSVNLEDI- 1606

  Fly   433 RTATVHELSSLLKRWLRELPQPLLTNELIQLFYQCHTLPSI-DQMNALSILCHLLPPENRNTLRS 496
               .||.|::|:|.:.|||.:|::..:|.:.|.....:..: :::..||::..|||..||..|..
 Worm  1607 ---GVHVLTTLVKAFFRELAEPIIIFDLYENFLNVSEVEDMGERVRCLSVMIELLPKPNRAVLDR 1668

  Fly   497 LLSFFNIIINLKDINKMNVHNVATIMAPSMFPPRYIHPSDNNSIAEQVRMAAQCCRLTNILILRG 561
            |:.....:.:.:.:|||..:|:|.|     |.|..:...|:....||:...|:.......||...
 Worm  1669 LMYHLARVADQEAVNKMGCNNLALI-----FGPCVLRRQDSAHAQEQLNDVARQTGCVQTLIEEK 1728

  Fly   562 EKLFQVPNNLIVE----SQKTMMGKKGWHRHRNSNEITAKPSGKASNVG 606
            .|.::...:.|||    |||.....:....||.::|    ||..:.|:|
 Worm  1729 LKQYKATIHNIVELEDASQKVSANLRKIEEHRRNSE----PSKFSPNIG 1773

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	56/224 (25%)
hum-7	NP_001248880.1	RA	28..134	CDD:214612
		MYSc	163..936	CDD:214580
		MYSc_Myo9	181..936	CDD:276836
		C1	1234..1284	CDD:237996
		C1	1475..1523	CDD:237996	12/76 (16%)
		RhoGAP	1540..1727	CDD:295372	52/203 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910